Irving-Rodgers H F, Rodgers R J
Research Centre for Reproductive Health, Department of Obstetrics and Gyneacology, University of Adelaide, Adelaide, Australia.
Ital J Anat Embryol. 2005;110(2 Suppl 1):225-30.
A Call-Exner body appears as a rosette of granulosa cells radially disposed (polarized) around an aggregate of extracellular matrix. The function of these bodies is unknown. A newly described matrix, focimatrix, also develops as aggregates of basal lamina-like material between granulosa cells. It appears much later in follicular development, and in a far greater amount than Call-Exner bodies. Its possible role is to reduce the polarity of epithelial granulosa cells allowing them to develop into non-polarized mesenchymal luteal cells upon ovulation of the follicle. Call-Exner bodies may arise from early and isolated expression of focimatrix.
Call-Exner小体表现为围绕细胞外基质聚集体呈放射状排列（极化）的颗粒细胞玫瑰花结。这些小体的功能尚不清楚。一种新描述的基质，即卵泡基质，也作为颗粒细胞之间类似基膜物质的聚集体而形成。它在卵泡发育后期出现，且数量远多于Call-Exner小体。其可能的作用是降低上皮颗粒细胞的极性，使它们在卵泡排卵时发育成非极化的间充质黄体细胞。Call-Exner小体可能源于卵泡基质的早期和孤立表达。
