Giles Thomas D, Materson Barry J
University of Miami School of Medicine, Miami, FL 3310, USA.
J Clin Hypertens (Greenwich). 2005 Aug;7(8):464-70. doi: 10.1111/j.1524-6175.2005.04535.x.
The prevalence of hypertension increases with advancing age, due primarily to increases in systolic blood pressure. Systolic hypertension is the most common form of hypertension in individuals over 50 years of age and reflects pathologic decreases in arterial compliance. Systolic blood pressure elevation is a more important risk factor for cardiovascular disease than is diastolic blood pressure elevation. Stage 2 hypertension, defined as blood pressure > or =160/100 mm Hg, is often found in older persons, who are at highest risk for cardiovascular events. In this clinical review, hypertension experts utilize a case study to provide a paradigm for treating older patients with stage 2 hypertension.
高血压的患病率随年龄增长而增加，主要原因是收缩压升高。收缩期高血压是50岁以上人群中最常见的高血压形式，反映了动脉顺应性的病理性降低。收缩压升高比舒张压升高是心血管疾病更重要的危险因素。2级高血压定义为血压≥160/100 mmHg，常见于老年人，他们发生心血管事件的风险最高。在本临床综述中，高血压专家利用一个病例研究为治疗老年2级高血压患者提供一个范例。
