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Burst activity and synaptic mechanisms in a hypothalamic network grown in culture.

作者信息

Misgeld U, Swandulla D

机构信息

I. Physiologisches Institut der Universität Heidelberg, FRG.

出版信息

Physiol Res. 1992;41(1):91-2.

PMID:1610786
Abstract

In a cultured network of rat embryonic hypothalamic cells, synaptic interaction is through GABAA-receptors, that mediate inhibition by an increase in Cl- conductance, and AMPA-receptors, that mediate excitation by an increase in monovalent cationic conductance. Changes in the balance of inhibition and excitation towards a predominance of excitation lead to phasic synchronous activity of the cells. Synaptic interaction through these receptors is thus capable of modulating neurosecretion rapidly.

摘要

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