[体外受精后出生的双胞胎的神经学晚期后遗症——二次发表。一项全国队列研究]
[Neurological late sequelae in twins born after in vitro fertilisation--secondary publication. A national cohort study].
作者信息
Pinborg Anja, Loft Anne, Schmidt Lone, Greisen Gorm, Rasmussen Steen, Andersen Anders Nyboe
机构信息
H:S Rigshospitalet, Fertilitetsklinikken og Neonatalklinikken, Københavns Universitet, Institut for Folkesundhedsvidenskab, ogSundhedsstyrelsen, Afdeling for Sundhedsstatistik.
出版信息
Ugeskr Laeger. 2005 Aug 15;167(33):3051-4.
Currently 4% of the Danish national birth cohort is born after in vitro fertilisation techniques and almost 40% of these children are twins. In this register-based national cohort study, twins from assisted conception (n = 3393) had a similar risk of neurological sequelae and cerebral palsy as their naturally conceived peers (n = 10.239) and assisted conceived singletons (n = 5130). Further children born after intracytoplasmic sperm injection (ICSI) had the same risk of neurological sequelae as children born after conventional IVF.
目前，丹麦全国出生队列中有4%的婴儿是通过体外受精技术出生的，其中近40%是双胞胎。在这项基于登记的全国队列研究中，辅助受孕的双胞胎（n = 3393）与自然受孕的同龄人（n = 10239）以及辅助受孕的单胎（n = 5130）患神经后遗症和脑瘫的风险相似。此外，胞浆内单精子注射（ICSI）后出生的儿童与传统体外受精后出生的儿童患神经后遗症的风险相同。
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