Chang Kai-Ping, Lee Li-Yu, Yeh Albert Re-Ming, Dai Tsung-Sung, Hao Sheng-Po
Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital and Chang Gung University, 14F, No.16, Alley 4, Lane 137, Min-Sheng E. Rd. Sec. 5, Taipei, Taiwan.
Head Neck. 2005 Nov;27(11):1004-7. doi: 10.1002/hed.20260.
Atypical carcinoid tumor is a neuroendocrine tumor; its occurrence in the larynx is uncommon, and clinical manifestations are rare. We report an unusual case of atypical carcinoid tumor of the epiglottis mimicking a supraglottic retention cyst.
A 44-year-old woman complained of an intermittent globus sensation of the throat of 2 years' duration. A 1.0- x 0.8-cm cystic lesion was found over the tip of the epiglottis. A supraglottic retention cyst was initially diagnosed, and the patient was treated medically. Her symptoms persisted, so we performed a laryngoscopic biopsy, which suggested an atypical carcinoid tumor.
Transoral endoscopic CO2 laser surgery and bilateral elective neck dissection were subsequently performed. The 2-year follow-up did not reveal any locoregional recurrence or distant metastasis.
This aggressive neoplasm may cause only a few, unremarkable symptoms and masquerade as a supraglottic cyst. Endoscopic CO2 laser surgery can be used to resect this uncommon tumor, with oncologically sound results and without surgical morbidity.
非典型类癌肿瘤是一种神经内分泌肿瘤;其在喉部的发生并不常见,临床表现也较为罕见。我们报告一例不寻常的会厌非典型类癌肿瘤病例,该肿瘤酷似声门上潴留囊肿。
一名44岁女性主诉有持续2年的间歇性咽部异物感。在会厌尖端发现一个1.0×0.8厘米的囊性病变。最初诊断为声门上潴留囊肿,并对患者进行了药物治疗。她的症状持续存在,因此我们进行了喉镜活检,结果提示为非典型类癌肿瘤。
随后进行了经口内镜二氧化碳激光手术及双侧选择性颈清扫术。2年的随访未发现任何局部区域复发或远处转移。
这种侵袭性肿瘤可能仅引起一些不明显的症状,并伪装成声门上囊肿。内镜二氧化碳激光手术可用于切除这种罕见肿瘤,肿瘤学效果良好且无手术并发症。