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准分子原位角膜磨镶术后铰链位置会影响干眼吗?

Does hinge position affect dry eye after laser in situ keratomileusis?

作者信息

Ghoreishi Mohammad, Aidenloo Naser Samadi, Peyman Alireza, Peyman Mohammadreza, Haghdoustoskoey Monireh

机构信息

Farabi Eye Hospital, Isfahan, Iran.

出版信息

Ophthalmologica. 2005 Sep-Oct;219(5):276-80. doi: 10.1159/000086111.

Abstract

PURPOSE

To evaluate the effect of corneal flap hinge position on dry eye after laser in situ keratomileusis (LASIK).

METHODS

In a prospective double-masked randomized controlled clinical trial, 212 consecutive eyes of 106 myopic patients underwent LASIK; in each patient, one eye was randomly assigned to the superior hinge and the other eye to the nasal hinge procedure. The patients were examined pre-operatively and 1 week, 1 month, 3 months and 6 months after surgery for visual acuity, fluorescein tear film breakup time and Schirmer's baseline tear secretion test; a subjective evaluation of dry eye symptoms was accomplished by the Ocular Surface Disease Index (OSDI) questionnaire at the 1-month, 3-month and 6-month postoperative visits.

RESULTS

Tear film breakup time was not significantly different with the nasal or superior hinge flap technique at the preoperative, 1-week, 1-month, 3-month and 6-month visits (p > 0.05 for all comparisons between two groups). No significant difference between the two groups was found for the amount of Schirmer's baseline tear secretion test at pre- and postoperative visits (p > 0.05 for all comparisons between two groups). Subjective evaluation of symptoms also showed no significant difference at the 1-month, 3-month and 6-month postoperative visits.

CONCLUSIONS

The nasal and superior hinge flap methods do not affect signs and symptoms of dry eye after LASIK. We recommend that selecting the hinge position should be done according to the surgeon's preference and ease.

摘要

目的

评估准分子原位角膜磨镶术(LASIK)中角膜瓣铰链位置对干眼的影响。

方法

在一项前瞻性双盲随机对照临床试验中,106例近视患者的212只眼连续接受了LASIK手术;每位患者的一只眼随机分配接受上方铰链手术,另一只眼接受鼻侧铰链手术。术前以及术后1周、1个月、3个月和6个月对患者进行视力、荧光素泪膜破裂时间和Schirmer基础泪液分泌试验检查;术后1个月、3个月和6个月通过眼表疾病指数(OSDI)问卷对干眼症状进行主观评估。

结果

术前、术后1周、1个月、3个月和6个月时,鼻侧或上方铰链瓣技术的泪膜破裂时间无显著差异(两组间所有比较p>0.05)。术前和术后访视时,两组间Schirmer基础泪液分泌试验量也无显著差异(两组间所有比较p>0.05)。症状的主观评估在术后1个月、3个月和6个月时也无显著差异。

结论

鼻侧和上方铰链瓣方法不影响LASIK术后干眼的体征和症状。我们建议应根据手术医生的偏好和操作便利性来选择铰链位置。

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