色素性嗜铬细胞瘤：1例经细针穿刺抽吸诊断的病例报告
Pigmented pheochromocytoma: report of a case with diagnosis by fine needle aspiration.
作者信息
Handa Uma, Khullar Urvashi, Mohan Harsh
机构信息
Department of Pathology, Government Medical College and Hospital, Chandigarh, India.
出版信息
Acta Cytol. 2005 Jul-Aug;49(4):421-3. doi: 10.1159/000326176.
BACKGROUND
Pheochromocytoma is a common tumor of the adrenal medulla, but its pigmented variant is rare.
CASE REPORT
A 38-year-old woman presented with complaints of abdominal pain. Ultrasound revealed a right suprarenal mass. Fine needle aspiration (FNA) smears showed the characteristic cytomorphology of pheochromocytoma, with melanin pigment in the cytoplasm. Melanin was differentiated from lipofuschin and hemosiderin by various histochemical stains. Histopathologic findings and immunohistochemical stains confirmed the diagnosis. To our knowledge, this is the first reported case of pigmented pheochromocytoma diagnosed on FNA.
CONCLUSION
FNA has proven to be a rapid and conclusive method of diagnosing pigmented pheochromocytoma, with no complications.
背景
嗜铬细胞瘤是肾上腺髓质的常见肿瘤，但其色素沉着型变体罕见。
病例报告
一名38岁女性因腹痛就诊。超声检查发现右肾上腺肿块。细针穿刺（FNA）涂片显示嗜铬细胞瘤的特征性细胞形态，细胞质中有黑色素。通过各种组织化学染色将黑色素与脂褐素和含铁血黄素区分开来。组织病理学检查结果和免疫组织化学染色证实了诊断。据我们所知，这是首例经FNA诊断的色素沉着型嗜铬细胞瘤病例。
结论
FNA已被证明是诊断色素沉着型嗜铬细胞瘤的一种快速且确定性的方法，且无并发症。
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