Nurzyńska-Flak Joanna, Kowalczyk Jerzy R
Klinika Hematologii i Onkologii Dzieciecej Akademii Medycznej w Lublinie.
Pol Merkur Lekarski. 2005 Jun;18(108):654-6.
The growth of a neoplasm results from interactions of various carcinogenic factors, also environmental ones, so incidence of cancers depends on the place of living. Purpose of the work was the comparative analysis of the number and morbidity of childhood cancers in children living in four former Provinces of Lublin Region of Poland.
The study included the population of children and young adolescents, aged 0-17, living in the area of four former Provinces--Biała Podlaska, Chełm, Lublin and Zamość--of the Lublin Region in the years 1988-1998. The analysis determined the number and incidence (Incidence Rate, IR) of all childhood cancers, the parameters were calculated for the whole population according to sex, age on diagnosis and the place of living-urban or rural regions.
Between 1988 and 1998 a total of 856 cases of childhood cancers were noted in Lublin region: 154 cases (IR--141.8 per million) in Biała Podlaska Province, 105 cases (IR--122.0) in Chełm, 403 cases (IR--121.5) in Lublin and 194 cases (IR--115.8) in Zamość. In the 11-year-period of examination the highest incidence was stated in Biała Podlaska Province, but not statistic substantially. Higher incidence revealed among boys (except Zamość Province). Incidence was higher in urban areas than in rural ones in Chełm and Zamość Provinces and the same in urban and rural areas in Biała Podlaska and Lublin Provinces.
肿瘤的生长源于各种致癌因素的相互作用,包括环境因素,因此癌症的发病率取决于居住地点。本研究的目的是对生活在波兰卢布林地区四个前省份的儿童期癌症的数量和发病率进行比较分析。
本研究纳入了1988 - 1998年期间居住在卢布林地区四个前省份——比亚瓦河畔波德拉斯卡、切尔姆、卢布林和扎莫希奇——的0至17岁儿童和青少年人群。分析确定了所有儿童期癌症的数量和发病率(发病率,IR),并根据性别、诊断时的年龄以及居住地点(城市或农村地区)对整个人群计算了这些参数。
1988年至1998年期间,卢布林地区共记录了856例儿童期癌症病例:比亚瓦河畔波德拉斯卡省154例(IR——每百万141.8例),切尔姆105例(IR——122.0),卢布林403例(IR——121.5),扎莫希奇194例(IR——115.8)。在11年的检查期内,比亚瓦河畔波德拉斯卡省的发病率最高,但无统计学显著差异。男孩中的发病率较高(扎莫希奇省除外)。切尔姆省和扎莫希奇省城市地区的发病率高于农村地区,比亚瓦河畔波德拉斯卡省和卢布林省城市和农村地区的发病率相同。
1)卢布林地区儿童期癌症发病率最高的是比亚瓦河畔波德拉斯卡省(无统计学显著差异),2)仅在切尔姆省和扎莫希奇省,城市地区的发病率高于农村地区。