Le Roux P, Quinque K, Bonnel A S, Le Luyer B
Service des urgences pédiatriques, groupe hospitalier, 76600 Le Havre, France.
Arch Pediatr. 2005 Aug;12 Suppl 2:S122-6. doi: 10.1016/s0929-693x(05)80027-2.
Extra-pulmonary tuberculosis (EPT) accounts for around 25% of cases of the disease, and around 20% in children. In Pott's disease and other forms of bone and joint involvement (globally 10-15% of EPT cases), modern imaging techniques like MRI scan have improved diagnosis and follow-up of treatment outcomes. Tuberculous meningitis has not disappeared even in BCG vaccinated children and remains a severe form of the disease. Techniques like the polymerase chain reaction and MRI contribute to an early diagnosis and controversy persists regarding the role of corticosteroid therapy in the treatment strategy. Other localisations are rare in children, including tuberculosis of the urogenital tract, infection of the digestive tract or pericarditis.
肺外结核(EPT)约占结核病病例的25%,在儿童中约占20%。在波特氏病和其他形式的骨与关节受累(全球范围内占EPT病例的10 - 15%)中,像磁共振成像(MRI)扫描这样的现代成像技术改善了诊断以及对治疗结果的随访。即使在接种卡介苗的儿童中,结核性脑膜炎也并未消失,仍然是该疾病的一种严重形式。聚合酶链反应和MRI等技术有助于早期诊断,并且关于皮质类固醇疗法在治疗策略中的作用仍存在争议。其他部位受累在儿童中较为罕见,包括泌尿生殖道结核、消化道感染或心包炎。