Mack R B, Katz S M, Amenta P S
Department of Pathology, Hahnemann University, Philadelphia, Pa.
J Am Osteopath Assoc. 1992 Jun;92(6):799-802.
Choriocarcinoma is a malignant germ cell tumor that usually arises from a previous gestation, but may also arise from germ cells anywhere along their known migratory pathway during fetal development. Gestational choriocarcinoma is highly sensitive to chemotherapy. This malignancy is known to undergo spontaneous regression of the primary tumor, which, in the face of metastases, may obscure the primary tumor site. The authors report the case of a patient with choriocarcinoma who was seen with pulmonary metastases and a single large lesion in the kidney 5 years posthysterectomy. The problems in resolving the primary site and the importance of a tissue diagnosis before nephrectomy are discussed.
绒毛膜癌是一种恶性生殖细胞肿瘤，通常起源于既往妊娠，但也可能起源于胎儿发育过程中生殖细胞沿其已知迁移途径的任何部位。妊娠性绒毛膜癌对化疗高度敏感。已知这种恶性肿瘤的原发肿瘤可自发消退，在存在转移的情况下，这可能会掩盖原发肿瘤部位。作者报告了一例绒毛膜癌患者的病例，该患者在子宫切除术后5年出现肺转移和肾脏单个大病灶。讨论了确定原发部位的问题以及肾切除术前组织诊断的重要性。
