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新西兰女大学生沙眼衣原体感染的患病率及危险因素

Prevalence and risk factors for Chlamydia trachomatis infection in female New Zealand university students.

作者信息

Baker Michael, Ortega-Benito Jose, Garret Nick, Bromhead Collette, Leslie Kathryn, MacDonald Jane, McNicholas Anne

机构信息

Institute of Environmental Science and Research Limited, Porirua.

出版信息

N Z Med J. 2005 Aug 12;118(1220):U1607.

Abstract

AIMS

To measure the prevalence of urogenital Chlamydia trachomatis infection in a sample of sexually active female university students, to identify risk factors associated with infection, and to measure the uptake of screening.

METHODS

Female students aged 18-25 years, presenting to a university student health service from March to October 2003, were invited to participate. Information on demographic details and sexual behaviour was collected with a self-completed questionnaire. The students were tested for Chlamydia infection using the Roche Amplicor CT/NG PCR test of first void urine specimens.

RESULTS

Chlamydia prevalence was 2.7% (19/715). Infection was associated with previous sexually transmitted infection (STI), non-European ethnicity, and irregular use of condoms. Most participants were not using condoms regularly despite the risk of STI. Screening was technically straightforward and the participation rate was 59.9% (718/1199).

CONCLUSIONS

New Zealand needs to develop and implement an adequately resourced and evidence-based Chlamydia control strategy. This strategy should contain national guidelines on screening in a range of settings, including universities, as well as strategies for primary prevention of Chlamydia and other STI. Clinicians treating university-aged students should consider opportunistic Chlamydia screening for all of those who are sexually active. Further research, preferably in conjunction with intervention studies, is essential to assess the prevalence of Chlamydia in other populations.

摘要

目的

测定有性活动的女大学生样本中泌尿生殖系统沙眼衣原体感染的患病率,确定与感染相关的危险因素,并测定筛查的接受情况。

方法

邀请2003年3月至10月到大学生健康服务中心就诊的18 - 25岁女学生参与。通过自填问卷收集人口统计学细节和性行为信息。使用罗氏Amplicor CT/NG聚合酶链反应检测首次晨尿标本中的衣原体感染情况。

结果

衣原体患病率为2.7%(19/715)。感染与既往性传播感染、非欧洲族裔以及不规律使用避孕套有关。尽管存在性传播感染风险,但大多数参与者未规律使用避孕套。筛查在技术上很简单,参与率为59.9%(718/1199)。

结论

新西兰需要制定并实施一项资源充足且基于证据的衣原体控制策略。该策略应包含在包括大学在内的一系列场所进行筛查的国家指南,以及衣原体和其他性传播感染的一级预防策略。治疗大学生年龄患者的临床医生应考虑对所有有性活动的人进行机会性衣原体筛查。进一步的研究,最好结合干预研究,对于评估其他人群中衣原体的患病率至关重要。

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