Lang S, Rotter N, Lorenzen A, Ihrler S, Eckel R, Hölzel D, Rasp G, Wollenberg B, Sommer K
Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsklinikum Schleswig-Holstein -- Campus Lübeck.
HNO. 2005 Oct;53(10):905-11; quiz 912-3. doi: 10.1007/s00106-005-1294-2.
Salivary gland carcinomas comprise a rare group of malignant tumors which are difficult to diagnose and treat due to their histopathologic diversity, variable clinical course and anatomic location, particularly with respect to the facial nerve. The present paper summarizes important features of these tumors, including recent advances in their management, i.e., diagnosis, surgery of the primary tumor, neck dissection, radiation therapy, and updates risk factors, criteria of malignancy, and prognostic variables, taking into account the relevant literature. Additionally, the present paper highlights briefly the survival rates of patients suffering from salivary gland carcinomas. The present overview is divided into two parts: the first is focused on epidemiology, etiology, criteria of malignancy, prognostic factors, and tumor classification, while part II discusses the diagnosis and therapy of salivary gland carcinomas.
涎腺癌是一类罕见的恶性肿瘤,由于其组织病理学的多样性、临床病程和解剖位置各异,尤其是涉及面神经时,使得其诊断和治疗都很困难。本文总结了这些肿瘤的重要特征,包括其治疗方面的最新进展,即诊断、原发肿瘤手术、颈部清扫、放射治疗,并考虑相关文献更新了危险因素、恶性标准和预后变量。此外,本文还简要强调了涎腺癌患者的生存率。本综述分为两部分:第一部分聚焦于流行病学、病因学、恶性标准、预后因素和肿瘤分类,而第二部分讨论涎腺癌的诊断和治疗。