Ben-Meir D, Yin M, Chow C W, Hutson J M
Department of Surgery, Royal Children's Hospital, Douglas Stephens Surgical Research Laboratory, Murdoch Children's Research Institute, University of Melbourne, Melbourne, Australia.
J Urol. 2005 Oct;174(4 Pt 1):1443-4. doi: 10.1097/01.ju.0000173070.60040.87.
Urethral polyps in girls are included in the differential diagnosis of interlabial masses. Only 6 cases have been described in the English literature to date and etiology is uncertain. We present 5 more cases and review the literature. We also propose an etiology for urethral polyps in young girls and compare polyps between girls and boys as well as older females.
The medical records of prepubertal girls with urethral polyps seen at our hospital between 1980 and 2003, including operative reports and followup, were reviewed. A senior pathologist re-inspected the specimens to confirm the diagnosis. A MEDLINE search of urethral polyps was performed.
We identified 5 girls 2 to 10 years old with urethral polyps. All girls presented with "vaginal" bleeding, 1 had recurrent urinary tract infections and vulvitis, 1 had urinary frequency, and 1 had painful voiding. The polyps were not site specific and were located in the distal, mid and proximal urethra. All polyps were excised and were found benign. Four girls were cured after 1 procedure, while in one girl the polyp reappeared. The patients were followed for 1 to 17 years and eventually became asymptomatic.
Urethral polyps in prepubertal girls are probably benign. We suggest that the etiology of most of polyps in girls is similar to those in older females, that is a prolapsing urothelium that has evolved into a polyp.
女童尿道息肉是阴唇间肿物鉴别诊断的一部分。迄今为止,英文文献中仅报道过6例,病因尚不确定。我们报告另外5例并复习文献。我们还提出了幼龄女童尿道息肉的病因,并比较了女童、男童及成年女性的息肉情况。
回顾1980年至2003年间我院收治的青春期前尿道息肉女童的病历,包括手术报告及随访情况。一位资深病理学家重新检查标本以确诊。对尿道息肉进行了医学文献检索。
我们确定了5例2至10岁患有尿道息肉的女童。所有女童均表现为“阴道”出血,1例有复发性尿路感染和外阴炎,1例有尿频,1例有排尿疼痛。息肉并非局限于特定部位,位于尿道远端、中段和近端。所有息肉均被切除,结果为良性。4例女童经一次手术治愈,而1例女童息肉复发。对患者随访1至17年,最终症状消失。
青春期前女童的尿道息肉可能是良性的。我们认为,大多数女童息肉的病因与成年女性相似,即脱垂的尿路上皮演变成息肉。