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与慢性肉芽肿病相关的唐菖蒲伯克霍尔德菌骨髓炎:病例报告及文献复习

Burkholderia gladioli osteomyelitis in association with chronic granulomatous disease: case report and review.

作者信息

Boyanton Bobby L, Noroski Lenora M, Reddy Hari, Dishop Megan K, Hicks M John, Versalovic James, Moylett Edina H

机构信息

Department of Pathology, Baylor College of Medicine, Houston, TX, USA.

出版信息

Pediatr Infect Dis J. 2005 Sep;24(9):837-9. doi: 10.1097/01.inf.0000177285.44374.dc.

Abstract

We describe a case of insidious small bone osteomyelitis and soft tissue abscess with Burkholderia gladioli in a 6-year-old Caucasian boy with chronic granulomatous disease. DNA sequencing of the 16S ribosomal RNA gene confirmed the bacterial identification. Clinical cure was achieved with a combination of antimicrobial therapy and surgical debridement. A review of infections caused by Burkholderia spp., other than Burkholderia cepacia complex, in pediatric patients with chronic granulomatous disease is provided.

摘要

我们描述了一例6岁患有慢性肉芽肿病的白人男孩发生的隐匿性小骨骨髓炎和软组织脓肿,病原体为唐菖蒲伯克霍尔德菌。16S核糖体RNA基因的DNA测序证实了细菌的鉴定。通过抗菌治疗和手术清创相结合实现了临床治愈。本文还对慢性肉芽肿病儿科患者中除洋葱伯克霍尔德菌复合体外的其他伯克霍尔德菌属引起的感染进行了综述。

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