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周期性失语发作作为部分性癫痫持续状态的一种不寻常表现。

Periodic episodes of aphasia as an unusual manifestation of partial status epilepticus.

作者信息

Hasegawa Takafumi, Shiga Yusei, Narikawa Koichi, Jin Kazutaka, Fujihara Kanae, Takeda Atsushi, Itoyama Yasuto

机构信息

Department of Neurology, Tohoku University School of Medicine, 1-1 Seiryo-Machi, Aoba-ku, Sendai, Japan.

出版信息

J Clin Neurosci. 2005 Sep;12(7):820-2. doi: 10.1016/j.jocn.2004.09.024.

Abstract

Recurrent episodes of aphasia due to partial status epilepticus is an uncommon clinical entity. We report here a 78-year-old-woman with episodic aphasia which occurred periodically. During the ictal period, she was conscious, but had difficulty in speech and could not comprehend verbal commands. The ictal EEG showed continuous spike and sharp waves over the left frontotemporal area. After the administration of antiepileptic drugs, her language activity returned to near the baseline level and the epileptic discharges were significantly reduced. Nonconvulsive partial status epilepticus should be considered in the differential diagnosis of recurrent aphasia, even if the symptoms occur periodically.

摘要

部分性癫痫持续状态所致的复发性失语是一种罕见的临床病症。我们在此报告一名78岁的女性,她出现周期性发作的失语症状。在发作期,她意识清醒,但言语困难,无法理解言语指令。发作期脑电图显示左侧额颞区有持续的棘波和尖波。给予抗癫痫药物治疗后,她的语言活动恢复到接近基线水平,癫痫放电明显减少。即使症状呈周期性发作,在复发性失语的鉴别诊断中也应考虑非惊厥性部分性癫痫持续状态。

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