Neubauer Birger, Mutzbauer Till S, Struck Niklas, Smith Hans-Jürgen, Tetzlaff Kay
See-Berufsgenossenschaft, Reimerstwiete 2, 20457, Hamburg, Germany.
Eur J Appl Physiol. 2005 Dec;95(5-6):454-63. doi: 10.1007/s00421-005-0011-x. Epub 2005 Sep 17.
Previous studies have inconsistently shown changes in expiratory flows and volumes as well as diffusion capacity of the lungs after single dives and several diving related occupational conditions were considered as possible underlying factors. In this study mechanical impedance of the airways was measured before and after simulated dives to non-invasively determine whether there is evidence for lung function impairment due to hyperbaric exposure. Thirty-three healthy male divers employing air self-contained underwater breathing apparatus were randomly assigned to dry and wet chamber dives in a cross-over design to 600 kPa ambient pressure (total duration 43 min, bottom time 15 min, water temperature 24 degrees C). Immediately before and after diving, oscillometric parameters-e. g. resistance and reactance of the respiratory tract-were measured at defined frequencies (5, 20 Hz). Spirometry was carried out as well (FVC, FEV(1), MEF 25-75). No significant changes between post-exposure values and baseline values were detected by respiratory impedance and spirometry. Diving in accordance to diving regulations and without excessive workload is not a source for acute obstructive lung function changes as the obtained oscillometric data suggested. Moreover this study could not confirm changes in spirometry after simulated diving exposure.
先前的研究结果并不一致,有的研究表明单次潜水后呼气流量和容积以及肺扩散能力会发生变化,并且几种与潜水相关的职业状况被视为可能的潜在因素。在本研究中,在模拟潜水前后测量气道的机械阻抗,以无创方式确定是否有证据表明高压暴露会导致肺功能受损。33名使用空气自给式水下呼吸器的健康男性潜水员被随机分配,采用交叉设计进行干式和湿式舱内潜水,至600 kPa环境压力(总时长43分钟,水底停留时间15分钟,水温24摄氏度)。在潜水前后即刻,在规定频率(5、20赫兹)下测量示波参数,例如呼吸道的阻力和电抗。同时也进行了肺活量测定(用力肺活量、第1秒用力呼气量、25%-75%用力呼气中期流量)。通过呼吸阻抗和肺活量测定未检测到暴露后值与基线值之间有显著变化。正如所获得的示波数据所示,按照潜水规定且无过度工作量的潜水并非急性阻塞性肺功能变化的来源。此外,本研究无法证实模拟潜水暴露后肺活量测定的变化。