McMeniman C J, Barker S C
Parasitology Section, School of Molecular and Microbial Sciences, University of Queensland, Brisbane 4072, Australia.
Heredity (Edinb). 2006 Jan;96(1):63-8. doi: 10.1038/sj.hdy.6800760.
We studied inheritance at three microsatellite loci in eight F, and two F2 families of the body (clothes) louse of humans, Pediculus humanus. The alleles of heterozygous female-parents were always inherited in a Mendelian fashion in these families. Alleles from heterozygous male-parents, however, were inherited in two different ways: (i) in a Mendelian fashion and (ii) in a non-Mendelian fashion, where males passed to their offspring only one of their two alleles, that is, 100% nonrandom transmission. In male body lice, where there was non-Mendelian inheritance, the paternally inherited set of alleles was eliminated. We interpret this pattern of inheritance as evidence for extreme transmission ratio distortion of paternal alleles in this species.
我们研究了人类体虱（衣虱） Pediculus humanus的八个F1和两个F2家族中三个微卫星位点的遗传情况。在这些家族中，杂合子母本的等位基因总是以孟德尔方式遗传。然而，来自杂合子父本的等位基因以两种不同方式遗传：（i）以孟德尔方式；（ii）以非孟德尔方式，即雄性仅将其两个等位基因中的一个传递给后代，也就是100%非随机传递。在存在非孟德尔遗传的雄性体虱中，父本遗传的等位基因组被消除。我们将这种遗传模式解释为该物种中父本等位基因极端传递比率扭曲的证据。
