Aali B S, Malekpour R, Nakheii N, Mehdizadeh A
Department of Obstetrics & Gynaecology, Kerman University of Medical Sciences, Kerman, Iran.
Cytopathology. 2005 Oct;16(5):252-5. doi: 10.1111/j.1365-2303.2005.00269.x.
To determine the diagnostic accuracy of cytology smears in distinguishing between tube and non-tube structures.
One hundred cytology smears of fallopian tube and non-tube structures (vessels, round and ovarian ligaments) were prepared from surgically removed uterus and fallopian tube specimens and stained by the Papanicolaou method. The slides were reviewed blindly by pathologists and interpreted as tube or non-tube structures. The results were compared to the histological examination of the same specimens.
Results indicated an overall accuracy of 97% with a specificity of 98% and sensitivity of 96% for cytology smears, taking histology as the gold standard. Positive and negative predictive values were 96.1% and 97.9%, respectively.
Cytology smears are a convenient and cost effective tool for laboratory confirmation of tubal sterilization. This method can reduce the costs of laboratory examination, especially in developing countries, where tubal sterilizations are done in large cohorts. However, histological slides remain the gold standard in cases of medicolegal problems.
确定细胞学涂片在区分输卵管结构与非输卵管结构方面的诊断准确性。
从手术切除的子宫和输卵管标本中制备100份输卵管及非输卵管结构(血管、圆韧带和卵巢韧带)的细胞学涂片,采用巴氏染色法染色。病理学家对玻片进行盲法评估,并判断为输卵管或非输卵管结构。将结果与相同标本的组织学检查结果进行比较。
以组织学为金标准,细胞学涂片的总体准确率为97%,特异性为98%,敏感性为96%。阳性预测值和阴性预测值分别为96.1%和97.9%。
细胞学涂片是用于实验室确认输卵管绝育的一种便捷且经济有效的工具。该方法可降低实验室检查成本,尤其是在进行大量输卵管绝育手术的发展中国家。然而,在法医学问题的病例中,组织学切片仍是金标准。