Leboeuf-Yde Charlotte, Axén Iben, Jones Jess James, Rosenbaum Annika, Løvgren Peter W, Halasz Laszlo, Larsen Kristian
The Back Research Center, Backcenter Funen and University of Southern Denmark, DK-5750 Ringe, Denmark.
J Manipulative Physiol Ther. 2005 Sep;28(7):472-8. doi: 10.1016/j.jmpt.2005.07.003.
(1) To describe the low back pain (LBP) pattern at baseline; (2) to describe the long-term outcome pattern; (3) to investigate the presence of distinct subgroups in relation to outcome; (4) to establish whether short-term outcome is a predictor of long-term outcome.
A 3- to 6- and 12- to 18-month, multicenter practice-based, prospective descriptive study was performed in private chiropractic practices in Sweden. Fifty-eight of 64 previously compliant chiropractors each recruited a maximum of 30 consecutive patients with LBP. Complete baseline clinical information was provided on 1054 patients, of which 93% were interviewed approximately 3 months later, and 57% responded to a questionnaire at approximately 12 months. Chiropractic treatment was decided by the treating chiropractor. Twelve descriptive subgroups were created based on (1) duration of LBP at baseline, (2) duration of LBP in the past year, and (3) LBP pattern in the past year. The predictive value was tested for outcome status at the fourth visit. Information on self-reported LBP status and improvement over the past months were collected.
Patients were spread in a U-shaped fashion from benign to severe with the 2 extreme groups being most prevalent. About half the participants reported "no LBP in the past week" at 3 months and somewhat fewer at 12 months. Almost 75% claimed to be definitely better at 3 months, and approximately 50% at 12 months. Specific predictive subgroups can be identified, mainly in relation to the past-year history of LBP. Improvement at the fourth visit is a predictor of long-term outcome.
Knowledge of specific subgroups may improve the quality of care and the selection of homogeneous study populations in clinical trials.
(1)描述基线时的腰痛(LBP)模式;(2)描述长期结果模式;(3)调查与结果相关的不同亚组的存在情况;(4)确定短期结果是否为长期结果的预测指标。
在瑞典的私人脊骨神经医学诊所开展了一项为期3至6个月以及12至18个月的多中心、基于实践的前瞻性描述性研究。64名之前符合要求的脊骨神经医学医生中,有58名每人最多连续招募30例LBP患者。为1054例患者提供了完整的基线临床信息,其中93%的患者在大约3个月后接受了访谈,57%的患者在大约12个月时对问卷做出了回应。脊骨神经医学治疗由主治医生决定。根据(1)基线时LBP的持续时间、(2)过去一年中LBP的持续时间以及(3)过去一年中的LBP模式创建了12个描述性亚组。对第四次就诊时的结果状态进行了预测价值测试。收集了关于自我报告的LBP状态以及过去几个月改善情况的信息。
患者从良性到严重呈U形分布,两个极端组最为常见。约一半的参与者在3个月时报告“过去一周无LBP”,12个月时报告的人数略少。近75%的人声称在3个月时明显好转,12个月时约为50%。可以识别出特定的预测亚组,主要与过去一年的LBP病史有关。第四次就诊时的改善是长期结果的预测指标。
了解特定亚组可能会提高护理质量,并有助于在临床试验中选择同质的研究人群。