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Eyeglass frame allergic contact dermatitis: does tacrolimus prevent recurrences?

作者信息

Nakada Tokio, Iijima Masafumi, Maibach Howard I

机构信息

Department of Dermatology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8666, Japan.

出版信息

Contact Dermatitis. 2005 Oct;53(4):219-21. doi: 10.1111/j.0105-1873.2005.00664.x.

Abstract

A 35-year-old man developed well-demarcated, oedematous and erosive erythematous lesions on the nasal bridge and retroauricular regions bilaterally. His eyeglass frame was repaired by an optician 2 weeks prior to symptom onset. Patch testing revealed a positive reaction to scrapings of nose pads and temples of the frame in petrolatum. Because the patient did not take our exhortation to change eyeglass frames, we advised him to cover their nose pads and temples with vinyl tape to prevent direct skin contact. Although topical corticosteroid therapy produced clinical resolution temporally, recurrences were not prevented. After starting tacrolimus ointment therapy, recurrence has not occurred for 9 months. Tacrolimus may be effective for allergic contact dermatitis patients who cannot avoid repeated allergen exposure, as it may not only reduce inflammation but inhibit recurrences.

摘要

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