Atencia Javier, Beebe David J
Department of Biomedical Engineering, University of Wisconsin-Madison, 1550 Engineering Drive, Rm 2142 ECB, Madison, Wisconsin WI 53706, USA.
Nature. 2005 Sep 29;437(7059):648-55. doi: 10.1038/nature04163.
The microfabrication technologies of the semiconductor industry have made it possible to integrate increasingly complex electronic and mechanical functions, providing us with ever smaller, cheaper and smarter sensors and devices. These technologies have also spawned microfluidics systems for containing and controlling fluid at the micrometre scale, where the increasing importance of viscosity and surface tension profoundly affects fluid behaviour. It is this confluence of available microscale engineering and scale-dependence of fluid behaviour that has revolutionized our ability to precisely control fluid/fluid interfaces for use in fields ranging from materials processing and analytical chemistry to biology and medicine.
半导体行业的微制造技术使整合日益复杂的电子和机械功能成为可能,为我们提供了体积越来越小、成本越来越低且功能越来越智能的传感器和设备。这些技术还催生了用于在微米尺度上容纳和控制流体的微流体系统,在该尺度下,粘度和表面张力的重要性不断增加,深刻影响着流体行为。正是现有的微尺度工程技术与流体行为的尺度依赖性的融合,彻底改变了我们精确控制流体/流体界面的能力,使其可应用于从材料加工、分析化学到生物学和医学等诸多领域。