血清素缺乏会缩短秀丽隐杆线虫向前移动的持续时间。
Serotonin deficiency shortens the duration of forward movement in Caenorhabditis elegans.
作者信息
Wakabayashi Tokumitsu, Osada Takashi, Shingai Ryuzo
机构信息
Laboratory of Bioscience, Faculty of Engineering, Iwate University, Iwate 020-8551, Japan.
出版信息
Biosci Biotechnol Biochem. 2005 Sep;69(9):1767-70. doi: 10.1271/bbb.69.1767.
Serotonin has been implicated in numerous behaviors in a wide variety of animals. We examined the effect of serotonin deficiency, induced by genetic perturbations and cell ablations, on the duration of Caenorhabditis elegans forward movement. Mutants with defective serotonin biosynthesis or worms with ablated serotonergic neurons showed a markedly decreased duration of forward movement, suggesting involvement of this neuromodulator in the regulation of the duration of worm locomotion.
血清素与多种动物的众多行为有关。我们研究了由基因干扰和细胞消融诱导的血清素缺乏对秀丽隐杆线虫向前运动持续时间的影响。血清素生物合成有缺陷的突变体或血清素能神经元被消融的线虫向前运动的持续时间明显缩短，这表明这种神经调节剂参与了线虫运动持续时间的调节。
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