Serago C F, Houdek P V, Bauer-Kirpes B, Lewin A A, Abitbol A A, Gonzalez-Arias S, Marcial-Vega V A, Schwade J G
Cancer Treatment Center, Baptist Hospital of Miami, Florida 33176.
Med Phys. 1992 Jan-Feb;19(1):181-5. doi: 10.1118/1.596931.
Stereotactic radiosurgery of the brain may be accomplished with a linear accelerator by performing several noncoplanar arcs of a highly collimated beam focused at a point. The shape of the radiation distribution produced by this technique is affected by the beam energy, field size, and the number and size of the arcs. The influence of these parameters on the resulting radiation distributions was analyzed by computing dose volume histograms for a typical brain. Dose volume functions were computed for: (a) the energy range of 4-24 MV x rays; (b) target sizes of 1-4 cm; and (c) 1-11 arcs and dynamic rotation. The dose volume histograms were found to be dependent on the number of arcs for target sizes of 1-4 cm. However, these differences were minimal for techniques with 4 arcs or more. The influence of beam energy on the dose volume histogram was also found to be minimal.
脑部立体定向放射外科手术可通过直线加速器来完成，即对高度准直的射束进行多条非共面弧形照射，使射束聚焦于一点。该技术产生的辐射分布形状受射束能量、射野大小以及弧形照射的数量和大小影响。通过计算典型脑部的剂量体积直方图，分析了这些参数对最终辐射分布的影响。针对以下情况计算了剂量体积函数：(a) 4 - 24 MV X射线的能量范围；(b) 1 - 4 cm的靶区大小；(c) 1 - 11条弧形照射和动态旋转。结果发现，对于1 - 4 cm的靶区大小，剂量体积直方图取决于弧形照射的数量。然而，对于4条或更多弧形照射的技术，这些差异极小。还发现射束能量对剂量体积直方图的影响也极小。
