Tafil-Klawe M, Laudencka A, Klawe J J, Miśkowiec I
Department of Physiology, Collegium Medicum in Bydgoszcz, Nicolaus-Copernicus-University in Toruń, Poland.
J Physiol Pharmacol. 2005 Sep;56 Suppl 4:223-6.
Several studies of sleep-breathing physiology have suggested that sleep deprivation may worsen obstructive sleep apnea. The aim of the study was to determine the direct effect of night work on breathing variables during sleep in fast-rotating shift workers. Twenty one men - police officers, fast-rotating shift workers, underwent polysomnography on 2 occasions: under a normal sleeping condition after day work and after sleep deprivations after night work. Both sleep studies were conducted within 2 to 3 weeks of each other. Approximately half of the group was tested under control conditions (day work) first, with the remaining subjects tested under sleep deprivation conditions (night work) first. After a night shift the subjects did not show a significantly different apnea-hypopnea-index (AHI). However, night work significantly increased several breathing variables recorded during sleep after it: total duration of obstructive apneas (OA) during REM sleep, mean duration of OA during arousal, total duration of OA during NREM sleep, apnea index during arousal, mean length of OA during sleep period time, total duration of OA during sleep period time, mean length of OA during total sleep time, mean length of hypopnea during REM sleep, total duration of hypopnea during sleep period time and during total sleep time, maximal length of central apnea and OA, and total sleep time. Night work does not favor obstructive sleep apnea episodes during sleep, but worsens many an obstructive sleep apnea variable, as measured by polysomnography.
多项睡眠呼吸生理学研究表明,睡眠剥夺可能会加重阻塞性睡眠呼吸暂停。本研究的目的是确定夜班工作对快速轮班工人睡眠期间呼吸变量的直接影响。21名男性——警察,快速轮班工人,接受了两次多导睡眠监测:一次是在白班工作后的正常睡眠条件下,另一次是在夜班工作后的睡眠剥夺后。两次睡眠研究在彼此相隔2至3周内进行。该组中约一半的受试者首先在对照条件下(白班工作)进行测试,其余受试者首先在睡眠剥夺条件下(夜班工作)进行测试。夜班后,受试者的呼吸暂停低通气指数(AHI)没有显著差异。然而,夜班工作显著增加了此后睡眠期间记录的几个呼吸变量:快速眼动睡眠期间阻塞性呼吸暂停(OA)的总时长、觉醒期间OA的平均时长、非快速眼动睡眠期间OA的总时长、觉醒期间的呼吸暂停指数、睡眠期OA的平均时长、睡眠期OA的总时长、总睡眠时间内OA的平均时长、快速眼动睡眠期间呼吸浅慢的平均时长、睡眠期和总睡眠时间内呼吸浅慢的总时长、中枢性呼吸暂停和OA的最长时长,以及总睡眠时间。夜班工作在睡眠期间并不利于阻塞性睡眠呼吸暂停发作,但通过多导睡眠监测测量,会使许多阻塞性睡眠呼吸暂停变量恶化。