那屈肝素注射后发生的医源性皮肤钙化症。

Iatrogenic calcinosis cutis following nadroparin injection.

作者信息

Giorgini Simonetta, Martinelli Canio, Massi Daniela, Lumini Annalisa, Mannucci Marco, Giglioli Leonetto

机构信息

Department of Dermatological Sciences, University of Florence, Florence, Italy.

出版信息

Int J Dermatol. 2005 Oct;44(10):855-7. doi: 10.1111/j.1365-4632.2005.02310.x.

DOI:10.1111/j.1365-4632.2005.02310.x

PMID:16207189

Abstract

Accumulation of calcium in the skin is usually classified as a group of disorders referred to as calcinosis cutis. We report the case of a patient who developed iatrogenic calcinosis at the site of subcutaneous administration of low-molecular-weight heparins (LMWH) as nadroparin. This is usually used for the prevention of deep venous thrombosis, especially following renal transplantation. The role of calcium content in nadroparin is discussed.

摘要

皮肤中钙的积累通常被归类为一组称为皮肤钙化症的疾病。我们报告了一例在皮下注射低分子量肝素（LMWH）那屈肝素部位发生医源性钙化症的患者。那屈肝素通常用于预防深静脉血栓形成，尤其是在肾移植后。本文讨论了那屈肝素中钙含量的作用。