Wang Zhong Gao, Li Chao
Xuan Wu Hospital and Vascular Institute, Capital University of Medical Sciences, Beijing, China.
J Endovasc Ther. 2005 Oct;12(5):588-93. doi: 10.1583/05-1539.1.
To present a preliminary experience with a single-branch endograft for excluding Stanford type B aortic dissections with entry tears adjacent to the left subclavian artery (LSA).
From February to August 2004, 16 symptomatic patients (15 men; mean age 57.8 years, range 41-73) having a Stanford B aortic dissection with a proximal tear <15 mm from the LSA orifice were treated with a single-branch thoracic endograft constructed of Z-shaped nitinol stents to which a Dacron graft had been sutured. The tubular main stent-graft had a branched segment connected to it for implantation in the LSA. The deployment method is the same as for a straight endograft except that the branch is deployed first in the LSA to stabilize the entire device. The main body of endograft is then deployed into the descending aorta to seal the tear, block flow from entering the false lumen, and enlarge the true lumen.
Sixteen branched endografts were deployed to seal the entry tears, with a technical success rate of 94% (15/16). One case was converted to surgery when the branch became trapped in the LSA at the left thoracic outlet. Two proximal endoleaks were treated with additional tubular endografts. All the proximal tears were sealed by the stent-grafts, and the compressed true lumens were widened. No paraplegia or distal organ or limb ischemia was noted, nor was there any mortality or complications. By 3 months post treatment, symptoms had abated, thrombosis had formed in the false lumen, and the true lumen had resumed its normal diameter in 15 of the 16 stent-graft patients. One patient has a distal re-entry at the level of the visceral arteries that is being observed.
The single-branch thoracic aortic endograft provides a simpler, safer, and more effective means of treating aortic dissections with entry tears in proximity to the LSA.
介绍使用单分支血管内移植物治疗左锁骨下动脉(LSA)附近存在入口撕裂的斯坦福B型主动脉夹层的初步经验。
2004年2月至8月,16例有症状的患者(15例男性;平均年龄57.8岁,范围41 - 73岁)患有斯坦福B型主动脉夹层,其近端撕裂距LSA开口小于15 mm,接受了由Z形镍钛诺支架构建并缝合了涤纶移植物的单分支胸主动脉内移植物治疗。管状主支架移植物连接有一个分支段,用于植入LSA。除了先将分支植入LSA以稳定整个装置外,其展开方法与直管型血管内移植物相同。然后将内移植物主体植入降主动脉以封闭撕裂口,阻止血流进入假腔,并扩大真腔。
16个分支内移植物被用于封闭入口撕裂,技术成功率为94%(15/16)。1例在左胸出口处分支被困于LSA时转为手术治疗。2例近端内漏用额外的管状血管内移植物治疗。所有近端撕裂均被支架移植物封闭,受压的真腔得以扩大。未发现截瘫或远端器官或肢体缺血,也无死亡或并发症发生。治疗后3个月时,16例支架移植物患者中有15例症状减轻,假腔内形成血栓,真腔恢复正常直径。1例患者在内脏动脉水平有远端再入口,正在观察中。
单分支胸主动脉内移植物为治疗LSA附近存在入口撕裂的主动脉夹层提供了一种更简单、更安全且更有效的方法。