Yon Valérie, Loas Gwenolé, Brien Denis
University Psychiatric Department, Pinel's Hospital, Amiens, France.
Psychiatry Res. 2005 Nov 15;137(1-2):93-102. doi: 10.1016/j.psychres.2004.11.010. Epub 2005 Oct 6.
The aim of this article was to explore the relationships between subjective experience (SE) and objective symptoms in schizophrenia. Exploratory principal component analysis was used to determine the latent organization of the variables. A group of 310 chronic patients with schizophrenia who met ICD-10 criteria for F20 schizophrenic disorder were included in the study. SE and objective symptoms were rated using, respectively, the 24-item version of the Frankfurt Complaint Questionnaire (FCQ-24) and the Positive and Negative Syndrome Scale (PANSS). An exploratory principal component analysis was performed on the correlation matrix comprising items from both the FCQ-24 and the PANSS. Using several guidelines to select the number of factors, the exploratory principal component analysis yielded a six-factor solution with no overlap of the significant factor loadings for the items from each scale. These six factors represent, respectively, the subjective, negative, positive, disorganization, hostility and anxious-depressive dimensions of the schizophrenic phenomenology. The findings support the view that SE is a construct that is separate and distinct from the objective symptomatology in schizophrenia.
本文旨在探讨精神分裂症患者主观体验(SE)与客观症状之间的关系。采用探索性主成分分析来确定变量的潜在结构。研究纳入了310名符合ICD - 10中F20精神分裂症诊断标准的慢性精神分裂症患者。分别使用24项版的法兰克福主诉问卷(FCQ - 24)和阳性与阴性症状量表(PANSS)对主观体验和客观症状进行评分。对包含FCQ - 24和PANSS项目的相关矩阵进行探索性主成分分析。通过多种准则来选择因子数量,探索性主成分分析得出了一个六因子解,各量表项目的显著因子载荷无重叠。这六个因子分别代表精神分裂症现象学的主观、阴性、阳性、紊乱、敌对和焦虑抑郁维度。研究结果支持以下观点:主观体验是一种与精神分裂症客观症状学相分离且不同的结构。