Graven Torbjørn, Dalen Håvard, Klykken Bjørnar, Gil Robert J
Kardiologisk seksjon, Sykehuset Levanger, 7600 Levanger.
Tidsskr Nor Laegeforen. 2005 Oct 6;125(19):2641-4.
A new syndrome, first described by the Japanese, presents as acute myocardial infarction. However, by closer examination it shows extensive akinesia in the apical and mid portions of the left ventricle, in the absence of significant coronary artery stenosis. Recently this syndrome has also been recognised outside Japan. The mechanism is unclear, but diffuse impairment of coronary microcirculation may play a role in the pathogenesis. Timely diagnosis of this potential lethal condition is mandatory, as it avoids the unnecessary risk of thrombolysis and allows adequate treatment to be started early. Diagnosis is also important for reassuring the patients that they have a good chance of complete recovery. We present three cases with this syndrome and discuss pathogenesis and clinical implications.
一种最初由日本人描述的新综合征,表现为急性心肌梗死。然而,经仔细检查发现,左心室心尖部和中部存在广泛运动不能,而冠状动脉无明显狭窄。最近,这种综合征在日本以外的地区也得到了确认。其发病机制尚不清楚,但冠状动脉微循环的弥漫性损害可能在发病过程中起作用。及时诊断这种潜在的致命疾病至关重要,因为这样可以避免不必要的溶栓风险,并能尽早开始适当的治疗。诊断对于让患者放心他们有完全康复的良好机会也很重要。我们展示了三例该综合征病例,并讨论了其发病机制和临床意义。