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吡啶二羧酸的可见及紫外相干拉曼光谱

Visible and UV coherent Raman spectroscopy of dipicolinic acid.

作者信息

Pestov Dmitry, Zhi Miaochan, Sariyanni Zoe-Elizabeth, Kalugin Nikolai G, Kolomenskii Alexandre A, Murawski Robert, Paulus Gerhard G, Sautenkov Vladimir A, Schuessler Hans, Sokolov Alexei V, Welch George R, Rostovtsev Yuri V, Siebert Torsten, Akimov Denis A, Graefe Stefanie, Kiefer Wolfgang, Scully Marlan O

机构信息

Institute for Quantum Studies, Texas A&M University, College Station, TX 77843-4242, USA.

出版信息

Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):14976-81. doi: 10.1073/pnas.0506529102. Epub 2005 Oct 10.

Abstract

We use time-resolved coherent Raman spectroscopy to obtain molecule-specific signals from dipicolinic acid (DPA), which is a marker molecule for bacterial spores. We use femtosecond laser pulses in both visible and UV spectral regions and compare experimental results with theoretical predictions. By exciting vibrational coherence on more than one mode simultaneously, we observe a quantum beat signal that can be used to extract the parameters of molecular motion in DPA. The signal is enhanced when an UV probe pulse is used, because its frequency is near-resonant to the first excited electronic state of the molecule. The capability for unambiguous identification of DPA molecules will lead to a technique for real-time detection of spores.

摘要

我们使用时间分辨相干拉曼光谱法从吡啶二羧酸(DPA)获取分子特异性信号,DPA是细菌芽孢的标记分子。我们在可见光和紫外光谱区域都使用了飞秒激光脉冲,并将实验结果与理论预测进行比较。通过同时在多个模式上激发振动相干性,我们观察到一个量子拍信号,该信号可用于提取DPA中分子运动的参数。当使用紫外探测脉冲时,信号会增强,因为其频率与分子的第一激发电子态接近共振。明确识别DPA分子的能力将带来一种实时检测芽孢的技术。

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