Ein Sigmund H, Langer Jacob C, Daneman Alan
Division of General Surgery, Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada.
J Pediatr Surg. 2005 Oct;40(10):1612-5. doi: 10.1016/j.jpedsurg.2005.06.001.
The aim of this study was to determine if the presence of an appendicolith is associated with an increased risk for recurrent appendicitis after nonoperative treatment of pediatric ruptured appendix with inflammatory mass or abscess.
Ninety-six pediatric patients (52 girls, 44 boys), aged 16 months to 17 years (average, 7 years), were managed between 1980 and 2003. All were treated nonoperatively with intravenous triple antibiotics for 5 to 21 days. All children had at least a 2-year follow-up. This study was approved by the hospital research ethics board.
Six children (6%) who became worse and 41 (46%) who had an interval appendectomy were eliminated from the study. The other 49 patients comprised the study group and received no further treatment. Twenty-eight (57%) had no recurrence, and 21 (43%) had a recurrence within 1 month to 2 years (average, 3 months). In the study group, 31 (63%) children had no appendicolith on radiological imaging and 18 (37%) had. Presence of an appendicolith was associated with a 72% rate of recurrent appendicitis compared with a recurrence rate of 26% in those with no appendicolith (chi2 test, P < .004).
We conclude that the patients with appendicolith should have an interval appendectomy.
本研究旨在确定阑尾结石的存在是否与小儿破裂性阑尾炎伴炎性肿块或脓肿非手术治疗后复发性阑尾炎风险增加相关。
1980年至2003年间对96例年龄在16个月至17岁(平均7岁)的儿科患者(52名女孩,44名男孩)进行了治疗。所有患者均接受静脉三联抗生素非手术治疗5至21天。所有儿童均至少随访2年。本研究获得医院研究伦理委员会批准。
6例病情恶化的儿童(6%)和41例行间隔期阑尾切除术的儿童(46%)被排除在研究之外。其余49例患者组成研究组,未接受进一步治疗。28例(57%)无复发,21例(43%)在1个月至2年内复发(平均3个月)。在研究组中,31例(63%)儿童影像学检查无阑尾结石,18例(37%)有阑尾结石。有阑尾结石的患者复发性阑尾炎发生率为72%,无阑尾结石患者的复发率为26%(卡方检验,P <.004)。
我们得出结论,有阑尾结石的患者应行间隔期阑尾切除术。