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新型椎间盘替代物的有限元研究

Finite element study of a novel intervertebral disc substitute.

作者信息

Noailly Jérôme, Lacroix Damien, Planell Josep A

机构信息

Catalan Reference Centre in BioEngineering (CREBEC), Biomechanics and Biomaterials Division, Technical University of Catalonia, Diagonal, Barcelona, Spain.

出版信息

Spine (Phila Pa 1976). 2005 Oct 15;30(20):2257-64. doi: 10.1097/01.brs.0000182319.81795.72.

Abstract

STUDY DESIGN

A new type of composite device with a similar structure to a natural lumbar intervertebral disc was modeled, and its mechanical interaction with a L3-L5 lumbar spine segment was studied by a finite element analysis.

OBJECTIVE

To identify the influence of the prosthesis on the biomechanical changes induced in a L3-L4 lumbar spine segment model after having substituted the physiologic L4-L5 intervertebral disc by the implant.

SUMMARY OF BACKGROUND DATA

In our societies, the large number of back pain cases highly motivates the investigation of intervertebral disc prostheses. Postoperative complications induced by spinal fusion showed that the mechanical properties of the novel components and its interactivity with the rest of the spine are a critical point.

METHODS

The prosthesis replaced the L4-L5 intervertebral disc within a previously developed L3-L5 lumbar spine segment physiologic model. The effect of loads in compression, flexion, extension, and axial rotation was simulated, and two types of vertebrae-implant contact were compared to the physiologic model.

RESULTS

Models with disc substitute are much stiffer than the physiologic model. In case of perfect contact with the adjacent vertebrae, the implant behaves like a physiologic intervertebral disc and respects the surrounding motion segment biomechanics. Although no traumatic loads were calculated within the adjacent vertebrae, bone remodeling would be expected in the trabecular bone.

CONCLUSION

By using numerical methods, this study allows prediction of the static mechanical behavior of a new device within a lumbar spine structure, which appears very useful for preclinical study.

摘要

研究设计

构建了一种结构与天然腰椎间盘相似的新型复合装置模型,并通过有限元分析研究其与L3 - L5腰椎节段的力学相互作用。

目的

确定在L3 - L4腰椎节段模型中,用该植入物替代生理状态的L4 - L5椎间盘后,假体对所诱导的生物力学变化的影响。

背景资料总结

在我们的社会中,大量的背痛病例极大地推动了对椎间盘假体的研究。脊柱融合术后的并发症表明,新型部件的力学性能及其与脊柱其他部分的相互作用是一个关键点。

方法

在先前建立的L3 - L5腰椎节段生理模型中,用假体替换L4 - L5椎间盘。模拟了压缩、屈曲、伸展和轴向旋转载荷的作用,并将两种类型的椎体 - 植入物接触情况与生理模型进行了比较。

结果

有椎间盘替代物的模型比生理模型刚度大得多。在与相邻椎体完美接触的情况下,植入物的表现类似于生理椎间盘,并符合周围运动节段的生物力学。尽管在相邻椎体中未计算出创伤性载荷,但预计小梁骨会发生骨重塑。

结论

通过使用数值方法,本研究能够预测腰椎结构内一种新装置的静态力学行为,这对临床前研究似乎非常有用。

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