Bansal R, Watson D K
Department of Orthopaedics, Wrexham Maelor Hospital, UK.
Int J Clin Pract. 2005 Nov;59(11):1283-8. doi: 10.1111/j.1742-1241.2005.00605.x.
Warfarin anti-coagulation can cause significant delay in acute surgical admissions. We reviewed fracture neck of femur patients operated over a period of 4 years in our unit. There was an average delay to surgery of 4.36 days in patients on warfarin as against an average delay of 1.78 days in patients not on warfarin (p < 0.001). The review was followed up with a questionnaire-based survey of consultant haematologists, and a general agreement towards a protocol-based use of vitamin K(1) was noted. The reasons for limited use of vitamin K(1) include the lack of studies and guidelines specifically addressing the pre-operative emergency admissions. We highlight a practical problem shared across different specialities and identify the areas for future studies.
华法林抗凝治疗可能会导致急性外科手术入院显著延迟。我们回顾了本单位4年间接受手术治疗的股骨颈骨折患者。服用华法林的患者手术平均延迟4.36天,而未服用华法林的患者平均延迟1.78天(p < 0.001)。此次回顾之后,对血液科顾问医生进行了问卷调查,结果发现大家普遍同意基于方案使用维生素K(1)。维生素K(1)使用受限的原因包括缺乏专门针对术前急诊入院的研究和指南。我们强调了一个不同专科都存在的实际问题,并确定了未来研究的领域。