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多导睡眠图检查患者中体位性睡眠呼吸暂停的患病率。

Prevalence of positional sleep apnea in patients undergoing polysomnography.

作者信息

Mador M Jeffery, Kufel Thomas J, Magalang Ulysses J, Rajesh S K, Watwe Veena, Grant Brydon J B

机构信息

Division of Pulmonary, Critical Care & Sleep Medicine, Section 111S, State University of New York at Buffalo, Veterans Administration Medical Center, Veterans Affairs Western New York Healthcare Sytem, Buffalo, NY 14215, USA.

出版信息

Chest. 2005 Oct;128(4):2130-7. doi: 10.1378/chest.128.4.2130.

Abstract

STUDY OBJECTIVES

The primary aim of this study was to determine the prevalence of positional obstructive sleep apnea using a functional definition. Positional sleep apnea was defined as a total apnea-hypopnea index (AHI) > or = 5 with a > 50% reduction in the AHI between the supine and nonsupine postures, and an AHI that normalizes (AHI < 5) in the nonsupine posture. A secondary aim was to determine if positional sleep apnea can be diagnosed accurately during a split-night study.

DESIGN

Retrospective chart review.

SETTING

Two sleep centers in Buffalo, NY, one a Veterans Affairs Western New York Healthcare System Sleep Center (VAWNY) and the other a freestanding ambulatory center (Associated Sleep Center [ASC]).

PATIENTS

Three hundred twenty-six patients from the VAWNY, including 57 patients who underwent a split-night study and 242 patients from the ASC who underwent polysomnography.

INTERVENTIONS

None.

MEASUREMENTS

Patient characteristics and sleep study results.

RESULTS

Positional sleep apnea was seen in 49 of 99 patients (49.5%) with mild sleep apnea (AHI, 5 to 15/h), 14 of 72 patients (19.4%) with moderate sleep apnea (AHI, 15 to 30/h), and 5 of 77 patients (6.5%) with severe sleep apnea (AHI > 30/h). Sufficient sleep (> 15 min) in both postures was not seen in 104 of 269 patients (38.7%) and 80 of 242 overnight studies (33.1%) at the VAWNY and ASC, respectively, and was not seen in 47 of 57 split-night studies (82.5%). The percentage of studies with insufficient sleep in both postures was significantly greater for split-night studies (p < 0.0001).

CONCLUSIONS

Positional sleep apnea is common particularly in patients with mild disease. Positional sleep apnea cannot usually be assessed during a split-night study.

摘要

研究目的

本研究的主要目的是使用功能性定义确定体位性阻塞性睡眠呼吸暂停的患病率。体位性睡眠呼吸暂停定义为总呼吸暂停低通气指数(AHI)≥5,仰卧位与非仰卧位之间AHI降低>50%,且非仰卧位时AHI恢复正常(AHI<5)。次要目的是确定在分夜研究期间能否准确诊断体位性睡眠呼吸暂停。

设计

回顾性病历审查。

地点

纽约州布法罗的两个睡眠中心,一个是退伍军人事务部西纽约医疗系统睡眠中心(VAWNY),另一个是独立的门诊中心(联合睡眠中心[ASC])。

患者

来自VAWNY的326名患者,包括57名接受分夜研究的患者,以及来自ASC的242名接受多导睡眠图检查的患者。

干预措施

无。

测量指标

患者特征和睡眠研究结果。

结果

99例轻度睡眠呼吸暂停(AHI为5至15次/小时)患者中有49例(49.5%)出现体位性睡眠呼吸暂停,72例中度睡眠呼吸暂停(AHI为15至30次/小时)患者中有14例(19.4%)出现体位性睡眠呼吸暂停,77例重度睡眠呼吸暂停(AHI>30次/小时)患者中有5例(6.5%)出现体位性睡眠呼吸暂停。在VAWNY和ASC,分别有269例患者中的104例(38.7%)和242例过夜研究中的80例(33.1%)在两种体位下均未获得足够睡眠(>15分钟),57例分夜研究中有47例(82.5%)未获得足够睡眠。分夜研究中两种体位睡眠不足的研究比例显著更高(p<0.0001)。

结论

体位性睡眠呼吸暂停很常见,尤其是在轻度疾病患者中。通常无法在分夜研究期间评估体位性睡眠呼吸暂停。

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