运动强度对间歇性跛行患者运动康复反应的影响。
The effect of exercise intensity on the response to exercise rehabilitation in patients with intermittent claudication.
作者信息
Gardner Andrew W, Montgomery Polly S, Flinn William R, Katzel Leslie I
机构信息
CMRI Metabolic Research Center, University of Oklahoma Health Sciences Center, Oklahoma City 73117, USA.
出版信息
J Vasc Surg. 2005 Oct;42(4):702-9. doi: 10.1016/j.jvs.2005.05.049.
PURPOSE
The purpose of this randomized trial was to compare the efficacy of a low-intensity exercise rehabilitation program vs a high-intensity program in changing physical function, peripheral circulation, and health-related quality of life in peripheral arterial disease (PAD) patients limited by intermittent claudication.
METHODS
Thirty-one patients randomized to low-intensity exercise rehabilitation and 33 patients randomized to high-intensity exercise rehabilitation completed the study. The 6-month exercise rehabilitation programs consisted of intermittent treadmill walking to near maximal claudication pain 3 days per week at either 40% (low-intensity group) or 80% (high-intensity group) of maximal exercise capacity. Total work performed in the two training regimens was similar by having the patients in the low-intensity group exercise for a longer duration than patients in the high-intensity group. Measurements of physical function, peripheral circulation, and health-related quality of life were obtained on each patient before and after the rehabilitation programs.
RESULTS
After the exercise rehabilitation programs, patients in the two groups had similar improvements in these measures. Initial claudication distance increased by 109% in the low-intensity group (P < .01) and by 109% in the high-intensity group (P < .01), and absolute claudication distance increased by 61% (P < 0.01) and 63% (P < .01) in the low-intensity and high-intensity groups, respectively. Furthermore, both exercise programs elicited improvements (P < .05) in peak oxygen uptake, ischemic window, and health-related quality of life.
CONCLUSION
The efficacy of low-intensity exercise rehabilitation is similar to high-intensity rehabilitation in improving markers of functional independence in PAD patients limited by intermittent claudication, provided that a few additional minutes of walking is accomplished to elicit a similar volume of exercise.
目的
本随机试验旨在比较低强度运动康复计划与高强度运动康复计划对因间歇性跛行而受限的外周动脉疾病（PAD）患者身体功能、外周循环及健康相关生活质量的改善效果。
方法
31例随机分配至低强度运动康复组和33例随机分配至高强度运动康复组的患者完成了本研究。为期6个月的运动康复计划包括每周3天在跑步机上间歇性行走至接近最大跛行疼痛程度，低强度组运动强度为最大运动能力的40%，高强度组为80%。通过让低强度组患者比高强度组患者运动更长时间，使两种训练方案的总运动量相似。在康复计划前后，对每位患者进行身体功能、外周循环及健康相关生活质量的测量。
结果
运动康复计划后，两组患者在这些指标上均有相似程度的改善。低强度组初始跛行距离增加了109%（P < 0.01），高强度组增加了109%（P < 0.01）；低强度组和高强度组的绝对跛行距离分别增加了61%（P < 0.01）和63%（P < 0.01）。此外，两种运动方案均使峰值摄氧量、缺血窗及健康相关生活质量得到改善（P < 0.05）。
结论
对于因间歇性跛行而受限的PAD患者，低强度运动康复在改善功能独立性指标方面的效果与高强度康复相似，前提是通过额外增加几分钟行走以达到相似的运动量。
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