Brown Wendy J, Ford Jessica H, Burton Nicola W, Marshall Alison L, Dobson Annette J
School of Human Movement Studies, The University of Queensland, Brisbane, Queensland, Australia.
Am J Prev Med. 2005 Nov;29(4):265-72. doi: 10.1016/j.amepre.2005.06.009.
Although many studies support an inverse association between physical activity (PA) and depressive symptoms, prospective relationships between these variables have been confounded by pre-existing psychological and physical health problems.
This study examined the dose-response relationships between self-reported PA and depressive symptoms, using cross-sectional and prospective data from a population-based cohort of middle-aged women who participated in the Australian Longitudinal Study on Women's Health (ALSWH) between 1996 and 2001. Participants completed three mailed surveys (S1, 1996; S2, 1998; S3, 2001), which included questions about time spent in walking, moderate- and vigorous-intensity PA, and measures of psychological health (Center for Epidemiologic Studies Depression scale [CESD-10], and Mental health [MH] subscale of the Short Form 36 survey). Relationships between previous (S1, S2), current (S3), and habitual (S1, S2, S3) PA and "depressive symptoms" were examined, adjusting for sociodemographic and health-related variables (n=9207).
Mean CESD-10 scores decreased, and MH scores increased with increasing levels of previous, current, and habitual activity. Odds ratios for CESD-10 scores > or =10 or MH scores < or =52 at S3 were 30% to 40% lower among women who reported the equivalent of > or =60 minutes of moderate-intensity PA per week, compared with those who reported less PA than this. Women who were in the lowest PA category at S1, but who subsequently reported > or =240 metabolic equivalent minutes (MET.mins) per week had lower odds of CESD-10 scores of > or =10 or MH scores < or =52 at S3 than those who remained in the very low PA category.
These data suggest that there is a clear relationship between increasing PA and decreasing depressive symptoms in middle-aged women, independent of pre-existing physical and psychological health.
尽管许多研究支持身体活动（PA）与抑郁症状之间存在负相关，但这些变量之间的前瞻性关系一直受到既往心理和身体健康问题的混淆。
本研究利用1996年至2001年间参与澳大利亚妇女健康纵向研究（ALSWH）的中年女性人群队列的横断面和前瞻性数据，研究自我报告的PA与抑郁症状之间的剂量反应关系。参与者完成了三次邮寄调查（S1，1996年；S2，1998年；S3，2001年），其中包括关于步行、中等强度和剧烈强度PA所花费时间的问题，以及心理健康测量（流行病学研究中心抑郁量表[CESD-10]和简短形式36调查的心理健康[MH]子量表）。研究了既往（S1、S2）、当前（S3）和习惯性（S1、S2、S3）PA与“抑郁症状”之间的关系，并对社会人口统计学和健康相关变量进行了调整（n=9207）。
随着既往、当前和习惯性活动水平的增加，CESD-10平均得分降低，MH得分升高。与报告PA少于此水平的女性相比，报告每周相当于≥60分钟中等强度PA的女性在S3时CESD-10得分≥10或MH得分≤52的比值比低30%至40%。在S1时处于最低PA类别的女性，但随后报告每周≥240代谢当量分钟（MET.mins），与那些仍处于极低PA类别的女性相比，在S3时CESD-10得分≥10或MH得分≤52的几率更低。
这些数据表明，中年女性PA增加与抑郁症状减轻之间存在明确关系，与既往的身体和心理健康无关。
