一名患黑尿症患者的星形细胞瘤与垂体腺瘤的关联。

The association of astrocytoma and pituitary adenoma in a patient with alcaptonuria.

作者信息

Abs R, Van Vyve M, Willems P J, Neetens I, Van der Auwera B, Van den Ende E, Van de Kelft E, Beckers A, Van Marck E, Martin J J

机构信息

Department of Endocrinology, University of Antwerp, Belgium.

出版信息

J Neurol Sci. 1992 Mar;108(1):32-4. doi: 10.1016/0022-510x(92)90184-m.

DOI:10.1016/0022-510x(92)90184-m

PMID:1624949

Abstract

A female patient with a juvenile pilocytic astrocytoma and a pituitary adenoma is described. The patient also has alcaptonuria, a rare inborn error of metabolism with autosomal recessive mode of inheritance. The association of these three disorders has never been reported previously. The possible existence of a common genetic factor in the development of both tumors and alcaptonuria is discussed.

摘要

本文描述了一名患有青少年毛细胞型星形细胞瘤和垂体腺瘤的女性患者。该患者还患有黑尿症，这是一种罕见的常染色体隐性遗传代谢性先天性疾病。此前从未有过这三种疾病关联的报道。本文讨论了肿瘤和黑尿症发生过程中可能存在共同遗传因素的情况。