Yeo Khung Keong, Beauvallet Suzanne, Mau Marjorie K, Seto Todd B
Department of Medicine, John A Burns School of Medicine, University of Hawaii, USA.
Clin Cardiol. 2005 Sep;28(9):429-32. doi: 10.1002/clc.4960280908.
Although Asians and Pacific Islanders (PI) make up the fastest growing ethnic group in the United States, little is known about the clinical characteristics, procedural success, and procedure-related complications of those who undergo percutaneous coronary interventions (PCI).
This study investigated PCI procedural success and procedural complications among PI and Asian patients in comparison with Caucasians.
We examined clinical characteristics, procedural success (post-PCI lesion < 50%) and procedure-related complications (hemorrhage, renal failure, myocardial infarction, stroke, bypass surgery, death) for all patients undergoing PCI at our hospital from January 1999 to June 2003.
Overall, 2,598 PCIs were performed--1,058 (39%) in Caucasians, 1,163 (43%) in Asians, and 377 (14%) in PIs. The mean age of PIs (59 +/- 11 years) was significantly lower than that of Caucasians (65 +/- 12 years) and Asians (66 +/- 12 years). The mean body mass index (26 +/- 5) of Asians was significantly lower, while that of PIs (31 +/- 7) was significantly higher than that of Caucasians (28 +/- 6). More Asians (33.3%) and PIs (40.5%) had diabetes mellitus than did Caucasians (19.9%). More Asians (71.6%) and PIs (76.1%) had hypertension than did Caucasians (61.9%). Renal failure was more prevalent in Asians and PIs (6.0 and 7.4%, respectively) than in Caucasians (3.8%). Other than a higher prevalence of disease involving the left anterior descending vessel in Asians (56.4%) compared with Caucasians (50.4%), angiographic features across the three races were similar. There was no significant difference in procedural success (approximately 94%) or procedure-related complications among Caucasians (6.4%), Asians (7.1%), and PIs (4.3%).
Although PIs and Asians have a substantially higher burden of comorbidities than Caucasians, race does not appear to influence PCI procedural success or procedure-related complications.
尽管亚裔和太平洋岛民在美国是增长最快的种族群体,但对于接受经皮冠状动脉介入治疗(PCI)的患者的临床特征、手术成功率及手术相关并发症却知之甚少。
本研究调查了太平洋岛民和亚裔患者与白种人相比的PCI手术成功率及手术并发症情况。
我们检查了1999年1月至2003年6月在我院接受PCI的所有患者的临床特征、手术成功率(PCI术后病变<50%)及手术相关并发症(出血、肾衰竭、心肌梗死、中风、搭桥手术、死亡)。
总体而言,共进行了2598例PCI手术,其中白种人1058例(39%),亚裔1163例(43%),太平洋岛民377例(14%)。太平洋岛民的平均年龄(59±11岁)显著低于白种人(65±12岁)和亚裔(66±12岁)。亚裔的平均体重指数(26±5)显著较低,而太平洋岛民的平均体重指数(31±7)显著高于白种人(28±6)。患有糖尿病的亚裔(33.3%)和太平洋岛民(40.5%)比白种人(19.9%)更多。患有高血压的亚裔(71.6%)和太平洋岛民(76.1%)比白种人(61.9%)更多。肾衰竭在亚裔和太平洋岛民中更为普遍(分别为6.0%和7.4%),高于白种人(3.8%)。与白种人(50.4%)相比,亚裔中累及左前降支血管的疾病患病率更高(56.4%),除此之外,三个种族的血管造影特征相似。白种人(6.4%)、亚裔(7.1%)和太平洋岛民(4.3%)在手术成功率(约94%)或手术相关并发症方面没有显著差异。
尽管太平洋岛民和亚裔的合并症负担比白种人高得多,但种族似乎并不影响PCI手术成功率或手术相关并发症。