Zhou Wei-xin, Wang Hao, Ruan Ying-mao, Yan Jun, Wei Yi-zhen, Liu Ying-long
Echocardiography Department, Fuwai Hospital, Cardiovascular Institute, CAMS and PUMC, Beijing 100037, China.
Zhonghua Er Ke Za Zhi. 2005 Oct;43(10):758-61.
The present study was designed to evaluate the clinical manifestations, surgical findings, pathologic types and treatment of cardiac tumor and to analyze the echocardiographic characteristics of the cases.
Records of 19 patients with cardiac tumors confirmed by operations and pathology at Fuwai Cardiovascular Hospital in Beijing, China between Jan, 1983 and Dec, 2003 were reviewed. Clinical and echocardiographic data of all patients were analyzed.
The median age of patients was 7 +/- 5 years, ranging from 5 months to 14 years. There were 8 male and 11 female cases. The surgical findings revealed that 57.9% (11 cases) of cardiac tumors were found in left heart, 36.8% (7 cases) in right heart, 5.3% (1 case) in two ventricles. The pathological study revealed that 17 cases (89.5%) were diagnosed as primary cardiac benign tumors including myxoma in 10 cases (52.6%), rhabdomyoma in 4 cases (21.1%), fibroma in 2 cases (10.5%) and lipoma in 1 case (5.3%). Two cases were diagnosed (10.5%) as cardiac malignant tumors including a primary cardiac rhabdomyosarcoma and a metastatic epithelioid sarcoma. By using echocardiography 11 cases were diagnosed as myxomas and rhabdomyoma (11/19, 57.9%), 8 cases were diagnosed as space occupying lesions of the heart or myxoma (8/19, 42.1%).
Myxomas are the most common heart tumors seen in infancy and childhood, followed in frequency by rhabdomyomas, fibromas and lipomas. Surgery is recommended for patients with refractory and severe clinical symptoms.
本研究旨在评估心脏肿瘤的临床表现、手术所见、病理类型及治疗方法,并分析病例的超声心动图特征。
回顾了1983年1月至2003年12月间在中国北京阜外心血管病医院经手术及病理确诊的19例心脏肿瘤患者的病历。分析了所有患者的临床及超声心动图资料。
患者的中位年龄为7±5岁,年龄范围为5个月至14岁。男性8例,女性11例。手术所见显示,57.9%(11例)的心脏肿瘤位于左心,36.8%(7例)位于右心,5.3%(1例)位于双心室。病理研究显示,17例(89.5%)被诊断为原发性心脏良性肿瘤,其中黏液瘤10例(52.6%)、横纹肌瘤4例(21.1%)、纤维瘤2例(10.5%)、脂肪瘤1例(5.3%)。2例(10.5%)被诊断为心脏恶性肿瘤,包括1例原发性心脏横纹肌肉瘤和1例转移性上皮样肉瘤。通过超声心动图检查,11例被诊断为黏液瘤和横纹肌瘤(11/19,57.9%),8例被诊断为心脏占位性病变或黏液瘤(8/19,42.1%)。
黏液瘤是婴幼儿及儿童期最常见的心脏肿瘤,其次为横纹肌瘤、纤维瘤和脂肪瘤。对于有难治性及严重临床症状的患者,建议手术治疗。