成人斯蒂尔病诊断两年后发生的慢性粒细胞白血病。

Chronic myelogenous leukemia that occurred two years after the diagnosis of adult Still's disease.

作者信息

Nakagawa Yoshifumi, Furusyo Norihiro, Taniai Hiroaki, Henzan Hideho, Tsuchihashi Takuya, Hayashi Jun

机构信息

Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan.

出版信息

Intern Med. 2005 Sep;44(9):994-7. doi: 10.2169/internalmedicine.44.994.

DOI:10.2169/internalmedicine.44.994

PMID:16258220

Abstract

A 25-year-old Japanese man was diagnosed with steroid-resistant Adult Still's Disease (ASD) in August 2000. No evidence of chronic myelogenous leukemia (CML) had been found during admissions in 2000 and 2001. In August 2002, he was diagnosed with CML with a peripheral white blood count of 69,940/microl and positivity for Philadelphia chromosome and BCR/ABL fusion gene on bone marrow aspiration. No case of CML was reported to develop from ASD. Because a diagnosis of ASD is based on the exclusion of other diseases, we must be cognizant of the possibility of the development of concurrent diseases.

摘要

一名25岁的日本男性于2000年8月被诊断为类固醇难治性成人斯蒂尔病（ASD）。在2000年和2001年住院期间未发现慢性粒细胞白血病（CML）的证据。2002年8月，他被诊断为CML，外周血白细胞计数为69,940/微升，骨髓穿刺显示费城染色体和BCR/ABL融合基因呈阳性。此前未报道过ASD发展为CML的病例。由于ASD的诊断是基于排除其他疾病，我们必须认识到并发其他疾病的可能性。