Koseki T
Department of Ophthalmology, Akita University School of Medicine, Japan.
Nippon Ganka Gakkai Zasshi. 1992 Jun;96(6):757-66.
The lamina suprachoroidea of the human choroid was examined by electron microscopy using both thin sections and freeze fracture replicas. The lamina suprachoroidea was composed of 5-10 layers of pigmented cells interspersed with multiple layers of flattened fibroblastic cells. Tight junctions, gap junctions and intermediate junctions were seen between the fibroblastic cells. Tight junctions did not reveal zonula occludens but predominantly isolated types were revealed, as well as several pore-like fenestrations in the attenuated cell processes of the fibroblasts. The characteristic morphological appearance of the lamina suprachoroidea might suggest that the aqueous humour may be able to leak into the extraocular tissues through it. However, the numerous cellular layers and also the junctional complexes between the fibroblasts of the lamina suprachoroidea are likely to produce more resistance to uveoscleral drainage. As the multi-layered arrangement of fibroblastic cells and pigmented cells in the lamina suprachoroidea did not show the cellular barrier, it may be possible that the extraocular substances are able to flow into the eye through it.
利用超薄切片和冷冻断裂复制品，通过电子显微镜对人脉络膜上腔进行了检查。脉络膜上腔由5 - 10层色素细胞组成，其间散布着多层扁平的成纤维细胞。在成纤维细胞之间可见紧密连接、缝隙连接和中间连接。紧密连接未显示闭锁小带，而是主要显示为孤立型，并且在成纤维细胞的减薄细胞突起中可见一些孔状窗孔。脉络膜上腔的特征性形态外观可能提示房水可能能够通过它渗漏到眼外组织中。然而，脉络膜上腔的众多细胞层以及成纤维细胞之间的连接复合体可能对葡萄膜巩膜引流产生更大的阻力。由于脉络膜上腔中成纤维细胞和色素细胞的多层排列未显示出细胞屏障，眼外物质有可能通过它流入眼内。
