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经腔内支架置入术和定向斑块旋切术治疗的隐静脉移植血管狭窄的急性和长期预后

Acute and long-term outcome of narrowed saphenous venous grafts treated by endoluminal stenting and directional atherectomy.

作者信息

Pomerantz R M, Kuntz R E, Carrozza J P, Fishman R F, Mansour M, Schnitt S J, Safian R D, Baim D S

机构信息

Charles A. Dana Research Institute, Boston, Massachusetts.

出版信息

Am J Cardiol. 1992 Jul 15;70(2):161-7. doi: 10.1016/0002-9149(92)91269-a.

Abstract

Angioplasty of the narrowed saphenous vein bypass grafts remains a difficult challenge. Over a 37-month period at this institution, 119 of 176 interventions (68%) on saphenous vein grafts (average age 8.3 years from bypass surgery to graft intervention) were performed using either directional coronary atherectomy (n = 35) or Palmaz-Schatz intracoronary stents (n = 84), representing 37% of all stents and 15% of all atherectomies during the study period, respectively. Of the 57 saphenous vein graft lesions treated with conventional balloon angioplasty during this period, 49 (86%) had 1 or more contraindications to stenting or directional atherectomy (thrombus, total occlusion, reference vessel less than 3 mm in diameter). The acute success rate was 99% for stents (1 failure to dilate) and 94% for directional atherectomy (2 failures to cross the lesion with the atherectomy device). Lumen diameter increased from 0.9 to 3.6 mm (reference vessel 3.6) for stents, and from 0.9 to 3.5 mm (reference 3.8) for atherectomy (for all comparisons, p = not significant), with no major complications (abrupt or subabrupt closure, emergent coronary bypass surgery, death, or Q-wave myocardial infarctions). During the same time period 50 of 57 vein grafts (88%) rejected for stenting or atherectomy were dilated successfully by conventional balloon angioplasty, with 3 patients (5%) requiring emergent coronary bypass surgery. Angiographic follow-up was available for 50 of 64 eligible patients (78%).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对狭窄的大隐静脉旁路移植血管进行血管成形术仍然是一项艰巨的挑战。在本机构的37个月期间,对176例大隐静脉移植血管进行了119次干预(68%)(从旁路手术到移植血管干预的平均时间为8.3年),其中使用定向冠状动脉斑块旋切术(n = 35)或帕尔马兹 - 施查茨冠状动脉内支架(n = 84),分别占研究期间所有支架的37%和所有斑块旋切术的15%。在此期间,用传统球囊血管成形术治疗的57例大隐静脉移植血管病变中,49例(86%)有1项或更多项支架置入或定向斑块旋切术的禁忌证(血栓、完全闭塞、参考血管直径小于3 mm)。支架置入的急性成功率为99%(1例扩张失败),定向斑块旋切术为94%(2例旋切装置未能通过病变)。支架置入后管腔直径从0.9 mm增加到3.6 mm(参考血管3.6 mm),斑块旋切术从0.9 mm增加到3.5 mm(参考血管3.8 mm)(所有比较,p = 无显著性差异),无重大并发症(急性或亚急性闭塞、急诊冠状动脉旁路手术、死亡或Q波心肌梗死)。在同一时期,57例因支架置入或斑块旋切术被拒绝的静脉移植血管中有50例(88%)通过传统球囊血管成形术成功扩张,3例患者(5%)需要急诊冠状动脉旁路手术。64例符合条件的患者中有50例(78%)有血管造影随访结果。(摘要截断于250字)

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