NOD2/CARD15基因突变能否预测肠道移植物抗宿主病并帮助我们理解克罗恩病？ - Suppr

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Can NOD2/CARD15 mutations predict intestinal graft-versus-host disease and aid our understanding of Crohn's disease?

作者信息

Rogler Gerhard, Holler Ernst

机构信息

Gastroenterological Unit, Department of Internal Medicine I, University of Regensburg, Germany.

出版信息

Nat Clin Pract Gastroenterol Hepatol. 2004 Dec;1(2):62-3. doi: 10.1038/ncpgasthep0042.

DOI:10.1038/ncpgasthep0042

PMID:16265048

Abstract

摘要

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Can NOD2/CARD15 mutations predict intestinal graft-versus-host disease and aid our understanding of Crohn's disease?

作者信息

Rogler Gerhard, Holler Ernst

机构信息

Gastroenterological Unit, Department of Internal Medicine I, University of Regensburg, Germany.

出版信息

Nat Clin Pract Gastroenterol Hepatol. 2004 Dec;1(2):62-3. doi: 10.1038/ncpgasthep0042.

DOI:10.1038/ncpgasthep0042

PMID:16265048

Abstract

摘要

相似文献

Can NOD2/CARD15 mutations predict intestinal graft-versus-host disease and aid our understanding of Crohn's disease?

Nat Clin Pract Gastroenterol Hepatol. 2004 Dec;1(2):62-3. doi: 10.1038/ncpgasthep0042.

Increased intestinal permeability and NOD2 variants in familial and sporadic Crohn's disease.

Aliment Pharmacol Ther. 2006 May 15;23(10):1455-61. doi: 10.1111/j.1365-2036.2006.02916.x.

NOD2 mutation and mice: no Crohn's disease but many lessons to learn.

Trends Mol Med. 2005 Jul;11(7):307-9. doi: 10.1016/j.molmed.2005.06.003.

CARD15/NOD2 mutations in Crohn's disease.

Ann N Y Acad Sci. 2006 Aug;1072:9-18. doi: 10.1196/annals.1326.011.

CARD15 and Crohn's disease.

J Gastroenterol Hepatol. 2004 Jul;19(7):830. doi: 10.1111/j.1440-1746.2004.03560.x.

NOD2 mutations and Crohn's disease: are Paneth cells and their antimicrobial peptides the link?

Gut. 2004 Nov;53(11):1558-60. doi: 10.1136/gut.2004.043307.

NOD2 in Crohn's disease--loss or gain of function mutations?

Neth J Med. 2005 Sep;63(8):286-7.

Molecular genetics of Crohn's disease.

Curr Opin Genet Dev. 2004 Jun;14(3):264-70. doi: 10.1016/j.gde.2004.04.004.

Mutations in innate immune system NOD2/CARD 15 and TLR-4 (Thr399Ile) genes influence the risk for severe acute graft-versus-host disease in patients who underwent an allogeneic transplantation.

Transplantation. 2006 Jan 27;81(2):247-54. doi: 10.1097/01.tp.0000188671.94646.16.

NOD2 and Crohn's disease: loss or gain of function?

Immunity. 2005 Jun;22(6):661-7. doi: 10.1016/j.immuni.2005.06.004.

引用本文的文献

NOD2 and Crohn's Disease Clinical Practice: From Epidemiology to Diagnosis and Therapy, Rewired.

Inflamm Bowel Dis. 2025 Feb 6;31(2):552-562. doi: 10.1093/ibd/izae075.

The intestinal microbiota: its role in health and disease.

Eur J Pediatr. 2015 Feb;174(2):151-67. doi: 10.1007/s00431-014-2476-2. Epub 2015 Jan 7.

Short template amplicon and multiplex megaprimer-enabled relay (STAMMER) sequencing, a simultaneous approach to higher throughput sequence-based typing of polymorphic genes.

Immunogenetics. 2010 Apr;62(4):253-60. doi: 10.1007/s00251-010-0432-5. Epub 2010 Mar 4.

Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients.

Intensive Care Med. 2007 Sep;33(9):1541-8. doi: 10.1007/s00134-007-0722-z. Epub 2007 Jun 9.