Yan Yong-jian, He Feng-sheng, Huang Jin-xiang, Liu Lin-gang, Zhang Hao, Cao Kong-jing, Xu Yong-chen, Zhang Xue-li, Meng Xiang-hong, Zhu Bing-liang, Tang Wen-hua, Li Zhi-hong
Shandong Institute of Occupational Disease, Jinan 250062, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2005 Oct;23(5):333-5.
To study the delayed effect on neuropsychopathy and its related factors after acute organophosphorus pesticides poisoning (AOPP).
Two hundred and fifty-seven cases of AOPP in the observation period were chosen to follow-up 2 months later from the 4 county hospitals in Shandong Province where the incidence of organophosphorus pesticide poisoning is high.
Nine cases of organophosphate induced delayed polyneuropathy (OPIDP) were found and the incidence rate was 3.5%. The occurrence of OPIDP were related to the need for emergent artificial respiration, and the degree of poisoning, and the kinds of organophosphorus pesticides (Ops). The positive rate of symptoms of peripheral nerves, central nerves and psychogeny except auditory and visual hallucination after poisoning was significantly higher than that before (P < 0.05). The patient's situation of health, economy and work became statistically worse (P < 0.05).
We found some had delayed effects on neuropsychopathy after AOPP which could debase the patient's life quality. The control measure should be administered as early as possible.
研究急性有机磷农药中毒（AOPP）后对神经精神病变的迟发性影响及其相关因素。
选取山东省4家有机磷农药中毒高发的县级医院在观察期内的257例AOPP患者，于2个月后进行随访。
发现9例有机磷中毒迟发性多发性神经病（OPIDP），发生率为3.5%。OPIDP的发生与是否需要紧急人工呼吸、中毒程度及有机磷农药种类有关。中毒后除视听幻觉外的外周神经、中枢神经及精神症状阳性率显著高于中毒前（P<0.05）。患者的健康、经济及工作状况在统计学上变差（P<0.05）。
我们发现AOPP后部分患者存在对神经精神病变的迟发性影响，这会降低患者生活质量。应尽早采取控制措施。
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