Kleinman I, Lowy F H
Centre for Bioethics, University of Toronto, Ontario, Canada.
Arch Intern Med. 1992 Jul;152(7):1484-8.
Living organ donation should be recognized as an ethical compromise to the principle of nonmaleficence (doing no harm), given the risks healthy donors are allowed to assume. Living organ donation should be reserved for situations in which there is no acceptable alternative. Increasing the availability of cadaveric organs is most desirable, since it would decrease (although probably not eliminate) the need for living organ transplantation and would provide organs (ie, hearts) that could not otherwise be obtained. We propose the development of an incentive-based Advance-Directive Organ Registry, in which all adults are encouraged to register their advance directive regarding organ donations. Those individuals agreeing to permit usable organs to be taken at the time of death would receive priority for organs generated by the program, should a transplant become necessary when there is a shortage of organs. The proposed Advance-Directive Organ Registry is firmly founded on the principles of autonomy, beneficence, and justice.
鉴于健康捐赠者需承担一定风险,活体器官捐赠应被视为对不伤害原则(即不造成伤害)的一种伦理妥协。活体器官捐赠应仅用于没有可接受替代方案的情况。增加尸体器官的可获取性是最为理想的,因为这将减少(尽管可能无法消除)活体器官移植的需求,并能提供通过其他方式无法获得的器官(如心脏)。我们提议建立一个基于激励机制的预嘱器官登记处,鼓励所有成年人登记他们关于器官捐赠的预嘱。那些同意在死亡时允许摘取可用器官的个人,在器官短缺且有必要进行移植时,将优先获得该项目产生的器官。提议的预嘱器官登记处牢固地建立在自主、行善和公正的原则基础之上。