鼻型韦格纳肉芽肿病与皮肤结节病——两种肉芽肿性疾病的罕见组合。

Nasal Wegener's and skin sarcoid--a rare combination of two granulomatous diseases.

作者信息

Kuttikat A, Saeed T, Chopra B, Chopra S, Chakravarty K

机构信息

Department of Rheumatology, Harold Wood Hospital, Barking, Havering and Redbridge Hospitals NHS Trust, Romford, RM3 OBE, Essex, UK.

出版信息

Clin Rheumatol. 2006 Nov;25(6):895-7. doi: 10.1007/s10067-005-0087-z. Epub 2005 Nov 10.

DOI:10.1007/s10067-005-0087-z

PMID:16283416

Abstract

Wegener's granulomatosis (WG) and sarcoidosis are two distinct granulomatous diseases characterized by multisystem involvement. We report a patient who initially presented with symptoms of limited WG predominantly affecting the nose, followed by a facial rash, which was histologically proven to be due to sarcoidosis. The sequential development of these two diseases in one patient is very rare, and to our knowledge, only one such case has been reported in the last 50 years (Am J Kidney Dis 28:893-898, 1996).

摘要

韦格纳肉芽肿病（WG）和结节病是两种不同的肉芽肿性疾病，其特征为多系统受累。我们报告了一名患者，该患者最初表现为主要累及鼻部的局限性WG症状，随后出现面部皮疹，组织学检查证实为结节病。这两种疾病在同一患者中先后发生的情况非常罕见，据我们所知，在过去50年中仅报道过1例（《美国肾脏病杂志》28:893 - 898，1996年）。