二尖瓣原发性滑膜肉瘤

Primary synovial sarcoma of the mitral valve.

作者信息

Miller Dylan V, Deb Arjun, Edwards William D, Zehr Kenton J, Oliveira Andre M

机构信息

Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA.

出版信息

Cardiovasc Pathol. 2005 Nov-Dec;14(6):331-3. doi: 10.1016/j.carpath.2005.05.002.

DOI:10.1016/j.carpath.2005.05.002

PMID:16286044

Abstract

Primary cardiac synovial sarcoma is a rare malignancy, comprising approximately 5% of cardiac sarcomas and less than 0.1% of all primary cardiac tumors. Herein, we describe a synovial sarcoma arising on the anterior mitral leaflet in a 66-year-old man. The histopathologic diagnosis was supported by the immunohistochemical profile and the presence of the SYT-SSX1 fusion transcript identified by molecular genetic studies.

摘要

原发性心脏滑膜肉瘤是一种罕见的恶性肿瘤，约占心脏肉瘤的5%，占所有原发性心脏肿瘤的比例不到0.1%。在此，我们描述了一名66岁男性二尖瓣前叶出现的滑膜肉瘤。组织病理学诊断得到免疫组化结果以及分子遗传学研究鉴定出的SYT-SSX1融合转录本的支持。