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一名患有骨髓增生异常综合征的中性粒细胞减少患者发生脓毒性肌内栓塞,并伴有无症状性脓毒性肺栓塞。

Septic intramuscular embolism in a neutropenic patient with myelodysplastic syndrome accompanied by asymptomatic septic pulmonary emboli.

作者信息

Yano Shingo, Usui Noriko, Asai Osamu, Dobashi Nobuaki, Osawa Hiroshi, Takei Yutaka, Takahara Shinobu, Ogasawara Yoji, Yamaguchi Yuko, Saito Takeshi, Minami Jiro, Kobayashi Masayuki

机构信息

Division of Hematology and Oncology, the Department of Internal Medicine, Jikei University School of Medicine, Tokyo.

出版信息

Intern Med. 2005 Oct;44(10):1100-2. doi: 10.2169/internalmedicine.44.1100.

Abstract

Septic embolisms are rare disorders which are associated with increased mortality and morbidity. We describe a rare case of septic intramuscular embolism accompanied by asymptomatic pulmonary embolism in a neutropenic patient. Methicillin-sensitive Staphylococcus aureus (S. aureus) was detected and multiple nodules were revealed in both thighs and lung. Although he was treated with sensitive antibiotics to .S. aureus, the symptoms remained unchanged during the neutropenic period. Fever subsided rapidly and his thigh pain disappeared after neutropenia resolved. A prompt diagnosis and optimal therapeutic decisions are critical for the reduction of mortality.

摘要

脓毒性栓塞是一种罕见的疾病,与死亡率和发病率的增加有关。我们描述了一例罕见的中性粒细胞减少患者发生的脓毒性肌内栓塞伴无症状肺栓塞的病例。检测到对甲氧西林敏感的金黄色葡萄球菌,双大腿和肺部均发现多个结节。尽管给予了对金黄色葡萄球菌敏感的抗生素治疗,但在中性粒细胞减少期间症状仍未改变。中性粒细胞减少症缓解后,发热迅速消退,大腿疼痛消失。及时诊断和做出最佳治疗决策对于降低死亡率至关重要。

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