Gupta Ramesh Kumar, Jain Manoj, Garg Rekha
Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow.
Indian J Pathol Microbiol. 2004 Oct;47(4):474-6.
Being immuno-suppressed, renal allograft recipients are at increased risk of contracting various infectious complications. Pneumocystis carinii pneumonia (PCP) is one of the important opportunistic infection causing high morbidity and mortality in these patients. Majority of studies has reported the occurrence of PCP during 6 months to one year after renal transplantation. This communication describes occurrence of PCP in five renal allograft recipients 10 weeks to 72 months after transplantation. In view of elusive presentation, strong clinical and radiological suspicion followed by direct demonstration of the organisms is essential for early diagnosis and prompt treatment. These observations also indicate that PCP is an emerging opportunistic infection in immuno-compromised patients in tropical countries.
由于免疫抑制,肾移植受者感染各种感染性并发症的风险增加。卡氏肺孢子虫肺炎(PCP)是这些患者中导致高发病率和死亡率的重要机会性感染之一。大多数研究报告称,PCP发生在肾移植后的6个月至1年。本文描述了5例肾移植受者在移植后10周 至72个月发生PCP的情况。鉴于其表现隐匿,强烈的临床和影像学怀疑,随后直接证实病原体对于早期诊断和及时治疗至关重要。这些观察结果还表明,PCP在热带国家的免疫功能低下患者中是一种新出现的机会性感染。