Taieb S, Ceugnart L, Gauthier H, Penel N, Vanseymortier L
Département d'Imagerie, Centre Régional de Lutte contre le Cancer Oscar-Lambret, 3, rue Frédéric-Combemale, BP 309, 59020 Lille cedex, France.
Cancer Radiother. 2006 Feb-Mar;10(1-2):78-82. doi: 10.1016/j.canrad.2005.09.029. Epub 2005 Nov 21.
After treatment of primary soft tissue sarcoma, a third of patients will develop local or distant (lung in 90% of cases) recurrence. For an individual patient, the issue of cancer recurrence is a binary event. However, when developing surveillance strategies for large groups of patients, knowledge of the risks (tumor biology, natural history of the disease), the benefits (potential efficacy of salvage therapy) and diagnosis test performances is necessary to formulate a rationale and resource effective follow-up algorithm.
原发性软组织肉瘤治疗后,三分之一的患者会出现局部或远处复发(90%的病例发生在肺部)。对于个体患者而言,癌症复发问题是一个二元事件。然而,在为大量患者制定监测策略时,了解风险(肿瘤生物学、疾病自然史)、益处(挽救治疗的潜在疗效)以及诊断检测性能,对于制定合理且资源有效的随访算法是必要的。