Bonvalot S, Vanel D, Le Cesne A, Terrier P, Le Péchoux C
Département de Chirurgie, Comité Sarcome, Institut Gustave-Roussy, 39, rue Camille-Desmoulins, 94805 Villejuif cedex, France.
Cancer Radiother. 2006 Feb-Mar;10(1-2):41-9. doi: 10.1016/j.canrad.2005.09.028. Epub 2005 Nov 21.
Retroperitoneal sarcomas comprise approximately 15% of all soft tissue sarcomas and 50% of all retroperitoneal tumours. Helical CT of the abdomen and pelvis, with selective use of MRI will establish the extent of the tumour, its retroperitoneal location, the degree of necrosis, and the evidence of metastasis. A CT guided core needle biopsy is the optimal pre operative tissue sampling. A complete surgical resection is the mainstay of the treatment with a rim of normal tissue that often requires removal of adjacent organs. The 5-year probability of local control is approximately 50%. The role of adjuvant therapy is evolving and at present should not be used outside the investigational setting.
腹膜后肉瘤约占所有软组织肉瘤的15%,占所有腹膜后肿瘤的50%。腹部和盆腔螺旋CT,选择性使用MRI,将确定肿瘤范围、其腹膜后位置、坏死程度及转移证据。CT引导下的粗针活检是最佳的术前组织取样方法。完整的手术切除是主要治疗手段,常需切除边缘正常组织及相邻器官。局部控制的5年概率约为50%。辅助治疗的作用正在演变,目前在非研究环境中不应使用。